关键词: Oncology access interventional radiology new devices nutrition techniques and procedures

来  源:   DOI:10.1177/11297298231225808

Abstract:
UNASSIGNED: Totally implantable central venous access ports, are required for various purposes, ranging from chemotherapy to nutrition. Port infection is a common complication. In many patients with port infection, the ports are removed because antibiotics are ineffective. We evaluated the risk factors associated with port removal due to port infection.
UNASSIGNED: By retrospective chart review, we collected data of 223 patients who underwent port removal for any reason. Port infection was defined as infection symptoms, such as fever; elevated white blood cell counts or C-reactive protein levels; or redness at the port site, in the absence of other infections, which improved with port removal. The characteristics of patients with or without port infection were compared using univariate (chi-squared test, t-test) and multivariate logistic regression analyses.
UNASSIGNED: We compared 172 patients without port infection to 51 patients with port infection. Univariate analysis identified sex (p = 0.01), body mass index (BMI) ⩽20 kg/m2 (p = 0.00004), diabetes mellitus (p = 0.04), and purpose of use (p = 0.0000003) as significant variables. However, male sex (p = 0.03, 95% confidence interval [CI]: 0.01-0.23), BMI ⩽20 kg m2 (p = 0.002, 95% CI: 0.06-0.29), and purpose of use (total parenteral nutrition (TPN); p = 0.000005, 95% CI: 0.31-0.76) remained significant using multivariate analysis. Moreover, the patients with short bowel syndrome and difficulty in oral intake tended to be infected easily. Additionally, Staphylococcus species were the most common microbes involved in port infection.
UNASSIGNED: Male sex, BMI ⩽20 kg/m2, and purpose of use as a TPN were risk factors for port infection. Ports should not be used for long duration of TPN or used only in exceptional cases.
摘要:
完全可植入的中心静脉接入端口,出于各种目的需要,从化疗到营养。港口感染是常见的并发症。在许多港口感染患者中,由于抗生素无效,端口被移除。我们评估了由于端口感染而导致的端口移除的危险因素。
通过回顾性图表回顾,我们收集了223例因任何原因接受端口移除的患者的数据.港口感染被定义为感染症状,如发热;白细胞计数或C反应蛋白水平升高;或港口红肿,在没有其他感染的情况下,通过端口移除来改进。使用单变量(卡方检验,t检验)和多变量逻辑回归分析。
我们比较了172例没有港口感染的患者和51例港口感染的患者。单变量分析确定性别(p=0.01),身体质量指数(BMI)20kg/m2(p=0.00004),糖尿病(p=0.04),和使用目的(p=0.0000003)作为显著变量。然而,男性(p=0.03,95%置信区间[CI]:0.01-0.23),BMI20kgm2(p=0.002,95%CI:0.06-0.29),和使用目的(总肠外营养(TPN);p=0.000005,95%CI:0.31-0.76)使用多变量分析仍然显着。此外,短肠综合征和口服困难的患者容易感染。此外,葡萄球菌是港口感染中最常见的微生物。
男性,BMI≥20kg/m2,作为TPN使用的目的是港口感染的危险因素。端口不应长时间使用TPN或仅在特殊情况下使用。
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