Abstract：
BACKGROUND: Abnormal cervical cytology is commonly observed in women living with HIV (WLWH).
METHODS: A cross-sectional study was conducted with 130 WLWH and 147 age-matched healthy controls, who underwent gynecological examinations at Beijing Ditan Hospital. The presence of abnormal cervical cytology in WLWH was predicted after performing a logistic regression analysis.
RESULTS: Multivariate logistic regression revealed three independent factors, among which CD4 cell counts of more than 350 cells/μL was the protective factor, while human papillomavirus infection and abnormal vaginal pH were the risk factors.
CONCLUSIONS: Vaginal microecological disorders can increase the risk of abnormal cervical cytology in WLWH.
METHODS: A cross-sectional study was conducted with 130 WLWH and 147 age-matched healthy controls, who underwent gynecological examinations at Beijing Ditan Hospital. The presence of abnormal cervical cytology in WLWH was predicted after performing a logistic regression analysis.
RESULTS: Multivariate logistic regression revealed three independent factors, among which CD4 cell counts of more than 350 cells/μL was the protective factor, while human papillomavirus infection and abnormal vaginal pH were the risk factors.
CONCLUSIONS: Vaginal microecological disorders can increase the risk of abnormal cervical cytology in WLWH.
摘要：
背景：感染HIV（WLWH）的妇女通常观察到宫颈细胞学异常。
方法：对130名WLWH和147名年龄匹配的健康对照进行了横断面研究，他在北京地坛医院做了妇科检查。在进行逻辑回归分析后，可以预测WLWH中异常宫颈细胞学的存在。
结果：多因素logistic回归显示了三个独立因素，其中CD4细胞计数超过350细胞/μL是保护因子，而人乳头瘤病毒感染和阴道pH异常是危险因素。
结论：阴道微生态紊乱可增加WLWH宫颈细胞学异常的风险。
方法：对130名WLWH和147名年龄匹配的健康对照进行了横断面研究，他在北京地坛医院做了妇科检查。在进行逻辑回归分析后，可以预测WLWH中异常宫颈细胞学的存在。
结果：多因素logistic回归显示了三个独立因素，其中CD4细胞计数超过350细胞/μL是保护因子，而人乳头瘤病毒感染和阴道pH异常是危险因素。
结论：阴道微生态紊乱可增加WLWH宫颈细胞学异常的风险。
