Abstract：
UNASSIGNED: Coronary artery lesions (CALs) are a major complication of Kawasaki disease (KD); however, data on CAL incidence and risk factors in recurrent KD are limited.
UNASSIGNED: Ninety-seven children with recurrent KD were retrospectively enrolled from 2013 to 2022, and CAL incidence was tracked during admission, discharge, and during follow-up.
UNASSIGNED: Initially, 27.8% had CAL at admission and discharge, declining to 7.2% at 12 months post-discharge. Most patients (66 of 97, 68.0%) did not exhibit CAL at any of the time points, 7 cases presented CAL at all time points, indicating a persistent CAL. The remaining 20 cases presented CAL at admission but recovered at discharge or during follow-up. Notably, transient CALs had presented at discharge, or during the follow-up, but finally resolved at 12 months after discharge. Notably, prior IVIG resistance and increased prothrombin time seemed associated with CAL in recurrent KD, suggesting they could help identify patients needing close monitoring.
UNASSIGNED: The study highlights decreasing CAL incidence over time in recurrent KD but with diverse patterns, emphasizing the importance of monitoring and further investigations to confirm these findings.
UNASSIGNED: Ninety-seven children with recurrent KD were retrospectively enrolled from 2013 to 2022, and CAL incidence was tracked during admission, discharge, and during follow-up.
UNASSIGNED: Initially, 27.8% had CAL at admission and discharge, declining to 7.2% at 12 months post-discharge. Most patients (66 of 97, 68.0%) did not exhibit CAL at any of the time points, 7 cases presented CAL at all time points, indicating a persistent CAL. The remaining 20 cases presented CAL at admission but recovered at discharge or during follow-up. Notably, transient CALs had presented at discharge, or during the follow-up, but finally resolved at 12 months after discharge. Notably, prior IVIG resistance and increased prothrombin time seemed associated with CAL in recurrent KD, suggesting they could help identify patients needing close monitoring.
UNASSIGNED: The study highlights decreasing CAL incidence over time in recurrent KD but with diverse patterns, emphasizing the importance of monitoring and further investigations to confirm these findings.
摘要：
■冠状动脉病变（CAL）是川崎病（KD）的主要并发症，然而,关于复发性KD的CAL发生率和危险因素的数据有限.
■从2013年到2022年，对97例复发性KD儿童进行回顾性登记，并在入院时跟踪CAL发病率。放电,在后续行动中。
■最初，27.8%的人在入院和出院时患有CAL，出院后12个月下降至7.2%。大多数患者（97名患者中的66名，68.0％）在任何时间点都没有表现出CAL，在所有时间点出现7例CAL，表示持久的CAL。其余20例患者在入院时出现CAL，但在出院或随访期间恢复。值得注意的是,瞬态CAL在出院时出现，或者在后续行动中，但最终在出院后12个月得到解决。值得注意的是,先前的IVIG抵抗和凝血酶原时间增加似乎与复发性KD的CAL相关，表明他们可以帮助识别需要密切监测的患者。结论：该研究强调了随着时间的推移，复发性KD的CAL发病率下降，但模式不同，强调监测和进一步调查以确认这些发现的重要性。
■从2013年到2022年，对97例复发性KD儿童进行回顾性登记，并在入院时跟踪CAL发病率。放电,在后续行动中。
■最初，27.8%的人在入院和出院时患有CAL，出院后12个月下降至7.2%。大多数患者（97名患者中的66名，68.0％）在任何时间点都没有表现出CAL，在所有时间点出现7例CAL，表示持久的CAL。其余20例患者在入院时出现CAL，但在出院或随访期间恢复。值得注意的是,瞬态CAL在出院时出现，或者在后续行动中，但最终在出院后12个月得到解决。值得注意的是,先前的IVIG抵抗和凝血酶原时间增加似乎与复发性KD的CAL相关，表明他们可以帮助识别需要密切监测的患者。结论：该研究强调了随着时间的推移，复发性KD的CAL发病率下降，但模式不同，强调监测和进一步调查以确认这些发现的重要性。
