PDF(Pubmed)
Abstract：
Despite the high effectiveness of HPV vaccines in preventing infection, vaccine hesitancy remains a concern, particularly in China. This study aimed to explore college students\' attitudes toward HPV vaccination and identify associated factors. Data was collected through a cross-sectional survey using self-administered questionnaires in four cities from May to June 2022. Chi-square tests and logistic regression analyses were conducted to identify factors. Additionally, an integrated structural equation model (SEM) based on the 3Cs (confidence, convenience, complacency) was developed to understand underlying factors contributing to hesitancy. The results from 2261 valid questionnaires were enlightening. A significant 89.47% (59.4% for females) considered HPV vaccination necessary, with 9.82% remaining neutral and only 0.71% deeming it unnecessary. Factors like higher education, being a medical student, residing in urban areas, having medical insurance, more extraordinary living expenses, a family history of tumors, and a solid understanding of HPV played a role in perceiving the vaccine as necessary. Among the 1438 female respondents, 84.36% had no hesitancy toward HPV vaccination, 13.53% expressed hesitancy, and 2.11% refused vaccination. Factors like age, understanding of HPV, medical staff recommendations, living expenses, and family history influenced hesitancy levels. SEM revealed that the 3Cs significantly affected vaccine hesitancy. Factors like price, booking process, vaccination times, trust in vaccines, medical staff recommendations, efficiency, and risk perception collectively influenced hesitancy. In conclusion, this study found high acceptance of HPV vaccination but acknowledged the complexity of hesitancy factors. It recommends medical staff disseminate scientific knowledge, offer recommendations, simplify booking procedures, and expand vaccination sites to address vaccine hesitancy effectively.
摘要：
尽管HPV疫苗在预防感染方面具有很高的有效性，疫苗犹豫仍然是一个令人担忧的问题，尤其是在中国。本研究旨在探讨大学生对HPV疫苗接种的态度及相关因素。数据是通过2022年5月至6月在四个城市使用自我管理问卷进行的横断面调查收集的。进行卡方检验和逻辑回归分析以确定因素。此外,基于3C的集成结构方程模型(SEM)(置信度，便利性，自满）的开发是为了了解导致犹豫的潜在因素。2261份有效问卷的结果具有启发性。89.47％（女性为59.4％）认为必须接种HPV疫苗，9.82%的人保持中立，只有0.71%的人认为这是不必要的。像高等教育这样的因素，作为一名医学生，居住在城市地区，有医疗保险,更多非凡的生活费用，有肿瘤家族史,对HPV的深入了解在必要时感知疫苗方面发挥了作用。在1438名女性受访者中，84.36％对HPV疫苗接种毫不犹豫，13.53%表示犹豫，2.11%拒绝接种疫苗。像年龄这样的因素，了解HPV,医务人员的建议，生活费,和家族史影响犹豫水平。SEM显示3Cs显著影响疫苗犹豫。价格等因素，预订流程,接种次数,对疫苗的信任，医务人员的建议，效率,和风险认知共同影响了犹豫。总之,这项研究发现HPV疫苗的接受度很高,但承认犹豫因素的复杂性.它建议医务人员传播科学知识，提供建议，简化预订程序，并扩大疫苗接种地点，以有效解决疫苗犹豫。
