PDF(Pubmed)
Abstract：
CD24 has emerged as a molecule of significant interest beyond the oncological arena. Recent studies have unveiled its surprising and diverse roles in various biological processes and diseases. This review encapsulates the expanding spectrum of CD24 functions, delving into its involvement in immune regulation, cancer immune microenvironment, and its potential as a therapeutic target in autoimmune diseases and beyond. The \'magic\' of CD24, once solely attributed to cancer, now inspires a new paradigm in understanding its multifunctionality in human health and disease, offering exciting prospects for medical advancements.
摘要：
CD24已成为肿瘤学领域以外的重要分子。最近的研究揭示了它在各种生物过程和疾病中令人惊讶的不同作用。这篇综述概括了CD24功能的扩展范围，深入研究其参与免疫调节，癌症免疫微环境，以及它作为自身免疫性疾病及其他治疗靶点的潜力。CD24的“魔力”曾经完全归因于癌症，现在激发了一种新的范式来理解它在人类健康和疾病中的多功能性，为医学进步提供了令人兴奋的前景。
