Abstract：
OBJECTIVE: To report visual acuity (VA) outcomes, intraoperative and postoperative complications of isolated cataract surgery in eyes with retinitis pigmentosa (RP), compared with non-RP-affected eyes.
METHODS: Retrospective clinical cohort study.
METHODS: A total of 113,389 eyes underwent cataract surgery between July 2003 and March 2015 at 8 clinical sites in the United Kingdom. Eyes with RP as the only comorbid pathology and eyes without any ocular comorbidities (controls) undergoing cataract surgery were compared. VA at 4 to 12 weeks postoperatively and rates of intraoperative and postoperative complications are reported.
RESULTS: Seventy-two eyes had RP. The mean age in the RP group was 57 ± 15 compared to 75 ± 10 in controls (P < .001). Females represented 46% of RP cases and 60% of controls (P = .06). Preoperative VA (mean LogMAR = 1.03 vs 0.59, P < .001) and postoperative VA (0.71 vs 0.14, P < .001) were worse in RP group. The mean VA gain was 0.25 ± 0.60 LogMAR in RP vs 0.43 ± 0.48 LogMAR in controls (P < .001). There were no significant differences in the rate of intraoperative pupil expansion use, posterior capsular tears, or zonular dialysis. Postoperative cystoid macular edema developed in 6.9% of RP eyes and 1% of controls (P < .001). The need for IOL repositioning or exchange was not statistically different between the two groups.
CONCLUSIONS: Cataract surgery can improve vision in eyes with RP and cataract. Intraoperative complications were similar to control eyes; however, RP eyes experienced more frequent postoperative cystoid macular edema.
METHODS: Retrospective clinical cohort study.
METHODS: A total of 113,389 eyes underwent cataract surgery between July 2003 and March 2015 at 8 clinical sites in the United Kingdom. Eyes with RP as the only comorbid pathology and eyes without any ocular comorbidities (controls) undergoing cataract surgery were compared. VA at 4 to 12 weeks postoperatively and rates of intraoperative and postoperative complications are reported.
RESULTS: Seventy-two eyes had RP. The mean age in the RP group was 57 ± 15 compared to 75 ± 10 in controls (P < .001). Females represented 46% of RP cases and 60% of controls (P = .06). Preoperative VA (mean LogMAR = 1.03 vs 0.59, P < .001) and postoperative VA (0.71 vs 0.14, P < .001) were worse in RP group. The mean VA gain was 0.25 ± 0.60 LogMAR in RP vs 0.43 ± 0.48 LogMAR in controls (P < .001). There were no significant differences in the rate of intraoperative pupil expansion use, posterior capsular tears, or zonular dialysis. Postoperative cystoid macular edema developed in 6.9% of RP eyes and 1% of controls (P < .001). The need for IOL repositioning or exchange was not statistically different between the two groups.
CONCLUSIONS: Cataract surgery can improve vision in eyes with RP and cataract. Intraoperative complications were similar to control eyes; however, RP eyes experienced more frequent postoperative cystoid macular edema.
摘要：
目的：报告视力（VA）结果，视网膜色素变性（RP）眼的孤立性白内障手术的术中和术后并发症，与非RP受累的眼睛相比。
方法：回顾性临床队列研究。
方法：2010年12月至2014年12月期间，共有113,389只眼在英国8个临床地点接受了白内障手术。比较了以RP为唯一合并症的眼睛和没有任何眼部合并症的眼睛（对照）进行白内障手术。报告了术后4-12周的VA以及术中和术后并发症的发生率。
结果：72只眼有RP。RP组的平均年龄为57±15，而对照组为75±10（p<0.001）。女性占RP病例的46％和对照组的60％（p=0.06）。术前VA（平均LogMAR=1.03vs0.59，p<0.001）和术后VA（0.71vs0.14，p<0.001）在RP中较差。RP的平均VA增益为0.25±0.60LogMAR，对照组为0.43±0.48LogMAR（p<0.001）。术中瞳孔扩大使用率无显著差异，后囊膜撕裂，或者带状透析.术后黄斑囊样水肿发生在6.9%的RP眼和1%的对照组(p<0.001)。两组之间对IOL重新定位或交换的需求没有统计学差异。
结论：白内障手术可以改善RP和白内障患者的视力。术中并发症与对照眼相似；然而，RP眼术后出现更频繁的黄斑囊样水肿。
方法：回顾性临床队列研究。
方法：2010年12月至2014年12月期间，共有113,389只眼在英国8个临床地点接受了白内障手术。比较了以RP为唯一合并症的眼睛和没有任何眼部合并症的眼睛（对照）进行白内障手术。报告了术后4-12周的VA以及术中和术后并发症的发生率。
结果：72只眼有RP。RP组的平均年龄为57±15，而对照组为75±10（p<0.001）。女性占RP病例的46％和对照组的60％（p=0.06）。术前VA（平均LogMAR=1.03vs0.59，p<0.001）和术后VA（0.71vs0.14，p<0.001）在RP中较差。RP的平均VA增益为0.25±0.60LogMAR，对照组为0.43±0.48LogMAR（p<0.001）。术中瞳孔扩大使用率无显著差异，后囊膜撕裂，或者带状透析.术后黄斑囊样水肿发生在6.9%的RP眼和1%的对照组(p<0.001)。两组之间对IOL重新定位或交换的需求没有统计学差异。
结论：白内障手术可以改善RP和白内障患者的视力。术中并发症与对照眼相似；然而，RP眼术后出现更频繁的黄斑囊样水肿。
