Abstract：
OBJECTIVE: This study aimed to illustrate the effect of malaria infection on red blood cell parameters in children and evaluate the diagnostic relevance of haematological parameters in predicting malaria.
METHODS: The studies were identified through databases like PubMed, Google Scholar, and Scopus to retrieve related articles. Fourteen studies were selected by literature search based on inclusion and exclusion criteria, and a meta-analysis on different red blood cell parameters was performed.
RESULTS: Haematocrit, haemoglobin concentration, and RBC count show statistically significant findings with p values of (<0.00001), (p<0.00001) and (p=0.0004), respectively. Other parameters like MCV, MCH, and MCHC show statistically non-significant results with p values of 0.21, 0.36, and 0.63, respectively.
CONCLUSIONS: Considering the above findings, the combination of haemoglobin concentration, haematocrit, and RBC counts could be used as reliable parameters to predict the presence of infection and included in the diagnostic strategy for malaria in children.
METHODS: The studies were identified through databases like PubMed, Google Scholar, and Scopus to retrieve related articles. Fourteen studies were selected by literature search based on inclusion and exclusion criteria, and a meta-analysis on different red blood cell parameters was performed.
RESULTS: Haematocrit, haemoglobin concentration, and RBC count show statistically significant findings with p values of (<0.00001), (p<0.00001) and (p=0.0004), respectively. Other parameters like MCV, MCH, and MCHC show statistically non-significant results with p values of 0.21, 0.36, and 0.63, respectively.
CONCLUSIONS: Considering the above findings, the combination of haemoglobin concentration, haematocrit, and RBC counts could be used as reliable parameters to predict the presence of infection and included in the diagnostic strategy for malaria in children.
摘要：
目的：本研究旨在说明疟疾感染对儿童红细胞参数的影响，并评估血液学参数在预测疟疾中的诊断相关性。
方法：这些研究是通过PubMed等数据库确定的，谷歌学者，和Scopus检索相关文章。根据纳入和排除标准，通过文献检索选择了14项研究，并对不同的红细胞参数进行了荟萃分析。
结果：血细胞比容，血红蛋白浓度，和红细胞计数显示统计学上显著的发现，p值为(<0.00001)，（p<0.00001）和（p=0.0004），分别。其他参数，如MCV，MCH,和MCHC显示统计学上无显著性结果,p值分别为0.21,0.36和0.63。
结论：考虑到上述发现，血红蛋白浓度的组合，血细胞比容,RBC计数可作为预测感染存在的可靠参数，并纳入儿童疟疾的诊断策略。
方法：这些研究是通过PubMed等数据库确定的，谷歌学者，和Scopus检索相关文章。根据纳入和排除标准，通过文献检索选择了14项研究，并对不同的红细胞参数进行了荟萃分析。
结果：血细胞比容，血红蛋白浓度，和红细胞计数显示统计学上显著的发现，p值为(<0.00001)，（p<0.00001）和（p=0.0004），分别。其他参数，如MCV，MCH,和MCHC显示统计学上无显著性结果,p值分别为0.21,0.36和0.63。
结论：考虑到上述发现，血红蛋白浓度的组合，血细胞比容,RBC计数可作为预测感染存在的可靠参数，并纳入儿童疟疾的诊断策略。
