METHODS: This cross-sectional study was conducted on the baseline data of participants who had Iranian nationality, were at least 1 year of residence in the area, aged within the age range of 35-70 years, and willed to participate from the Fasa Persian Adult Cohort Study (FACS). IAD for systolic and diastolic blood pressure was measured and categorized into two groups of difference < 10 and ≥ 10 mmHg. Logistic regression was used to model the association between independent variables and IAD.
RESULTS: The prevalence of systolic and diastolic IAD ≥ 10 mmHg was 16.34% and 10.2%, respectively, among 10,124 participants. According to the multivariable logistic regression models, age (adjusted odds ratio (aOR): 1.019 [95% CI: 1.013, 1.025]), body mass index (BMI) (aOR: 1.112 [95% CI: 1.016, 1.229]), having type 2 diabetes (aOR Yes/No: 1.172 [95% CI: 1.015, 1.368]), having chronic headaches (aOR Yes/No: 1.182 [95% CI: 1.024, 1.365]), and pulse rate (aOR: 1.019 [95% CI: 1.014, 1.024]) significantly increased the odds of systolic IAD ≥ 10 mmHg. Additionally, high socio-economic status decreased the odds of systolic IAD ≥ 10 mmHg (aOR High/Low: 0.854 [95% CI: 0.744, 0.979]). For diastolic IAD, age (aOR: 1.112 [95% CI: 1.015, 1.210]) and pulse rate (aOR: 1.021 [95% CI: 1.015, 1.027]) significantly increased the odds of diastolic IAD ≥ 10 mmHg. Moreover, high socioeconomic status decreased the odds of diastolic IAD ≥ 10 mmHg (aOR High/Low: 0.820 [95% CI: 0.698, 0.963]).
CONCLUSIONS: The noticeable prevalence of systolic and diastolic IAD in general population exhibits health implications due to its\' association with the risk of cardiovascular events. Sociodemographic and medical history assessments have potentials to be incorporated in IAD risk stratification and preventing programs.
方法:这项横断面研究是根据具有伊朗国籍的参与者的基线数据进行的,在该地区至少居住了一年,年龄在35-70岁之间,并愿意参加法萨波斯成人队列研究(FACS)。测量收缩压和舒张压的IAD,并将其分为两组,差异<10和≥10mmHg。使用Logistic回归对自变量与IAD之间的关联进行建模。
结果:收缩期和舒张期IAD≥10mmHg的患病率分别为16.34%和10.2%,分别,在10,124名参与者中。根据多变量逻辑回归模型,年龄(调整后赔率比(AOR):1.019[95%CI:1.013,1.025]),体重指数(BMI)(AOR:1.112[95%CI:1.016,1.229]),患有2型糖尿病(AOR是/否:1.172[95%CI:1.015,1.368]),患有慢性头痛(aOR是/否:1.182[95%CI:1.024,1.365]),和脉搏率(aOR:1.019[95%CI:1.014,1.024])显著增加收缩期IAD≥10mmHg的几率。此外,高社会经济地位降低了收缩期IAD≥10mmHg的几率(aOR高/低:0.854[95%CI:0.744,0.979]).对于舒张期IAD,年龄(aOR:1.112[95%CI:1.015,1.210])和脉搏率(aOR:1.021[95%CI:1.015,1.027])显著增加舒张期IAD≥10mmHg的几率。此外,高社会经济地位降低了舒张期IAD≥10mmHg的几率(aOR高/低:0.820[95%CI:0.698,0.963]).
结论:在普通人群中,显著的收缩期和舒张期IAD患病率显示出健康意义,因为其与心血管事件风险相关。社会人口统计学和病史评估有可能纳入IAD风险分层和预防计划。