PDF(Pubmed)
Abstract：
UNASSIGNED: The objective of this systematic review is to analyse the randomised control trials (RCTs) comparing the self-gripping mesh (SGM) with sutured mesh fixation (SMF) in open inguinal hernia repair.
UNASSIGNED: RCTs comparing SGM with SMF in open inguinal hernia repair were selected from medical electronic databases and analysis was performed using the principles of meta-analysis with RevMan version 5 statistical software.
UNASSIGNED: Seventeen RCTs involving 3863 patients were used for the final analysis. In the random effect model analysis, the operative time [mean difference - 7.72, 95 %, CI (-9.08, -6.35), Z = 11.07, P = 0.00001] was shorter for open inguinal hernia repair with SGM. However, there was noteworthy heterogeneity (Tau2 = 4.24; Chi2 = 1795.04, df = 12; (P = 0.00001; I2 = 99 %) among the included studies. The incidence of chronic groin pain [odds ratio 1.17, 95 %, CI (0.88, 1.54), Z = 1.09, P = 0.28], postoperative complications [odds ratio 0.92, 95 %, CI (0.73, 1.16), Z = 0.71, P = 0.48] and recurrence [odds ratio 1.31, 95 %, CI (0.80, 2.12), Z = 1.08, P = 0.28] were statistically similar between both groups, without heterogeneity.
UNASSIGNED: SGM failed to demonstrate a clinical advantage over SMF in terms of perioperative outcomes although the duration of surgery was shorter in SGM.
UNASSIGNED: RCTs comparing SGM with SMF in open inguinal hernia repair were selected from medical electronic databases and analysis was performed using the principles of meta-analysis with RevMan version 5 statistical software.
UNASSIGNED: Seventeen RCTs involving 3863 patients were used for the final analysis. In the random effect model analysis, the operative time [mean difference - 7.72, 95 %, CI (-9.08, -6.35), Z = 11.07, P = 0.00001] was shorter for open inguinal hernia repair with SGM. However, there was noteworthy heterogeneity (Tau2 = 4.24; Chi2 = 1795.04, df = 12; (P = 0.00001; I2 = 99 %) among the included studies. The incidence of chronic groin pain [odds ratio 1.17, 95 %, CI (0.88, 1.54), Z = 1.09, P = 0.28], postoperative complications [odds ratio 0.92, 95 %, CI (0.73, 1.16), Z = 0.71, P = 0.48] and recurrence [odds ratio 1.31, 95 %, CI (0.80, 2.12), Z = 1.08, P = 0.28] were statistically similar between both groups, without heterogeneity.
UNASSIGNED: SGM failed to demonstrate a clinical advantage over SMF in terms of perioperative outcomes although the duration of surgery was shorter in SGM.
摘要：
■本系统评价的目的是分析比较自扣式网片（SGM）和缝合网片固定（SMF）在开放式腹股沟疝修补术中的随机对照试验（RCT）。
■从医学电子数据库中选择比较SGM和SMF在开放式腹股沟疝修补术中的RCT，并使用RevMan5版统计软件的荟萃分析原则进行分析。
■对包含3863名患者的17项随机对照试验进行最终分析。在随机效应模型分析中，手术时间[平均差异-7.72，95%，CI（-9.08，-6.35），Z=11.07，P=0.00001]对于采用SGM的开放式腹股沟疝修补术较短。然而,纳入研究中存在显著的异质性(Tau2=4.24;Chi2=1795.04,df=12;(P=0.00001;I2=99%).慢性腹股沟疼痛的发生率[比值比1.17，95%，CI（0.88，1.54），Z=1.09,P=0.28],术后并发症[比值比0.92，95%，CI（0.73，1.16），Z=0.71，P=0.48]和复发[比值比1.31，95%，CI（0.80，2.12），Z=1.08,P=0.28]两组间差异有统计学意义,没有异质性。
■尽管SGM的手术时间较短，但在围手术期结局方面，SGM未能显示出优于SMF的临床优势。
■从医学电子数据库中选择比较SGM和SMF在开放式腹股沟疝修补术中的RCT，并使用RevMan5版统计软件的荟萃分析原则进行分析。
■对包含3863名患者的17项随机对照试验进行最终分析。在随机效应模型分析中，手术时间[平均差异-7.72，95%，CI（-9.08，-6.35），Z=11.07，P=0.00001]对于采用SGM的开放式腹股沟疝修补术较短。然而,纳入研究中存在显著的异质性(Tau2=4.24;Chi2=1795.04,df=12;(P=0.00001;I2=99%).慢性腹股沟疼痛的发生率[比值比1.17，95%，CI（0.88，1.54），Z=1.09,P=0.28],术后并发症[比值比0.92，95%，CI（0.73，1.16），Z=0.71，P=0.48]和复发[比值比1.31，95%，CI（0.80，2.12），Z=1.08,P=0.28]两组间差异有统计学意义,没有异质性。
■尽管SGM的手术时间较短，但在围手术期结局方面，SGM未能显示出优于SMF的临床优势。
