PDF(Pubmed)
Abstract：
Abiotrophia defectiva is a type of Streptococci and is a rare cause of infectious endocarditis. The progression and outcomes of infectious intracranial aneurysms (IIAs) associated with this species are unknown due to a limited number of reported cases. A woman in her 20s with a sudden headache had a subarachnoid haemorrhage on a head CT scan. Cerebral angiography showed an aneurysm on the right middle cerebral artery. She was diagnosed with infectious endocarditis caused by A. defectiva and underwent parent artery occlusion. Despite initiating targeted antibiotic therapy, a new IIA developed and ruptured 14 days postadmission. A second parent artery occlusion was performed on the new IIA. Following 6 weeks of continued antibiotic therapy, she underwent mitral valve repair and was discharged with no neurological symptoms. Endocarditis caused by A. defectiva can lead to the delayed formation of an IIA. Endovascular treatment was effective for repeated ruptured IIAs.
摘要：
无亲变性是链球菌的一种，是感染性心内膜炎的罕见原因。由于报道的病例数量有限，与该物种相关的感染性颅内动脉瘤（IIAs）的进展和结果未知。一名20多岁突然头痛的妇女在头部CT扫描中出现蛛网膜下腔出血。脑血管造影显示右侧大脑中动脉有动脉瘤。她被诊断为由A引起的感染性心内膜炎。尽管开始了靶向抗生素治疗，新的IIA在入院后14天出现并破裂.对新的IIA进行了第二次母动脉闭塞。持续抗生素治疗6周后，她接受了二尖瓣修复术，出院后无神经症状。由A引起的心内膜炎可导致IIA的延迟形成。血管内治疗对反复破裂的IIA有效。
