PDF(Pubmed)
Abstract：
BACKGROUND: Oral Lichen Planus is a common chronic inflammatory disease of the oral mucosa. The prevalence in adults ranges between 0.5% and 2%, while in children is reported to be about 0,03%. Clinical features of Oral Lichen Planus could be variable in both adults and children, ranging from painless white hyperkeratotic lesions to painful erythematous atrophic ones. Actually, there are no systematic reviews in the literature on OLP in children, whereby this paper aims to summarize all the pathophysiological aspects and identify all cases described in the literature of Oral Lichen Planus in children, reporting their clinical characteristics.
METHODS: A systematic review of the literature was performed in online databases including PubMed, Scopus, Web of Science, Science Direct, EMBASE. In addition, in order to identify reports not otherwise identifiable, an analysis of the gray literature was performed on google scholar and in Open Gray.
RESULTS: By literature analysis, it emerged that most cases were reported from India. The mean age at time of diagnosis of the disease was 11 years, ranging from 3 to 17 years. The most frequent pattern was the reticular pattern followed by plaque-like, erosive, atrophic, sclerosus, and bullous. The buccal mucosa was the most involved oral site, followed by the tongue, lips and gingiva.
CONCLUSIONS: Although Oral Lichen Planus in children is rare, it may cause oral discomfort and need to be differentiated from other oral white lesions and/or chronic ulcers.
METHODS: A systematic review of the literature was performed in online databases including PubMed, Scopus, Web of Science, Science Direct, EMBASE. In addition, in order to identify reports not otherwise identifiable, an analysis of the gray literature was performed on google scholar and in Open Gray.
RESULTS: By literature analysis, it emerged that most cases were reported from India. The mean age at time of diagnosis of the disease was 11 years, ranging from 3 to 17 years. The most frequent pattern was the reticular pattern followed by plaque-like, erosive, atrophic, sclerosus, and bullous. The buccal mucosa was the most involved oral site, followed by the tongue, lips and gingiva.
CONCLUSIONS: Although Oral Lichen Planus in children is rare, it may cause oral discomfort and need to be differentiated from other oral white lesions and/or chronic ulcers.
摘要：
背景：口腔扁平苔藓是一种常见的口腔粘膜慢性炎症性疾病。成年人的患病率在0.5%到2%之间，而在儿童中，据报道约为0,03%。口腔扁平苔藓的临床特征在成人和儿童中都是可变的，从无痛性白色角化过度病变到疼痛性红斑萎缩性病变。事实上,关于儿童OLP的文献中没有系统的评论，本文旨在总结所有病理生理方面，并确定儿童口腔扁平苔藓文献中描述的所有病例，报告其临床特征。
方法：在包括PubMed，Scopus,WebofScience,科学直接，Embase.此外,为了识别无法以其他方式识别的报告，在谷歌学者和OpenGray中对灰色文献进行了分析。
结果：通过文献分析，据报道，大多数病例来自印度。确诊时平均年龄为11岁,从3到17年不等。最常见的模式是网状模式，其次是斑块状，侵蚀性,萎缩性,硬化,还有bullous.口腔黏膜是最受累的口腔部位，接着是舌头，嘴唇和牙龈。
结论：尽管儿童口腔扁平苔藓很少见，它可能会导致口腔不适，需要与其他口腔白色病变和/或慢性溃疡区分开来。
方法：在包括PubMed，Scopus,WebofScience,科学直接，Embase.此外,为了识别无法以其他方式识别的报告，在谷歌学者和OpenGray中对灰色文献进行了分析。
结果：通过文献分析，据报道，大多数病例来自印度。确诊时平均年龄为11岁,从3到17年不等。最常见的模式是网状模式，其次是斑块状，侵蚀性,萎缩性,硬化,还有bullous.口腔黏膜是最受累的口腔部位，接着是舌头，嘴唇和牙龈。
结论：尽管儿童口腔扁平苔藓很少见，它可能会导致口腔不适，需要与其他口腔白色病变和/或慢性溃疡区分开来。
