Abstract：
The auditory afferent pathway as a clinical marker of Alzheimer\'s disease (AD) has sparked interest in investigating the relationship between age-related hearing loss (ARHL) and AD. Given the earlier onset of ARHL compared to cognitive impairment caused by AD, there is a growing emphasis on early diagnosis and intervention to postpone or prevent the progression from ARHL to AD. In this context, auditory evoked potentials (AEPs) have emerged as a widely used objective auditory electrophysiological technique for both the clinical diagnosis and animal experimentation in ARHL due to their non-invasive and repeatable nature. This review focuses on the application of AEPs in AD detection and the auditory nerve system corresponding to different latencies of AEPs. Our objective was to establish AEPs as a systematic and non-invasive adjunct method for enhancing the diagnostic accuracy of AD. The success of AEPs in the early detection and prediction of AD in research settings underscores the need for further clinical application and study.
摘要：
听觉传入通路作为阿尔茨海默病（AD）的临床标志物，引起了人们对研究年龄相关性听力损失（ARHL）与AD之间关系的兴趣。考虑到与AD引起的认知障碍相比，ARHL的发作更早，人们越来越重视早期诊断和干预,以延缓或防止ARHL进展为AD.在这种情况下，听觉诱发电位（AEP）由于其非侵入性和可重复的性质，已成为ARHL临床诊断和动物实验中广泛使用的客观听觉电生理技术。本文就AEPs在AD检测中的应用以及AEPs不同潜伏期对应的听觉神经系统作一综述。我们的目标是建立AEP作为一种系统的，非侵入性的辅助方法，以提高AD的诊断准确性。AEP在研究环境中早期发现和预测AD方面的成功强调了进一步临床应用和研究的需要。
