Abstract：
UNASSIGNED: Corticosteroid injections are frequently used in the short-term treatment of musculoskeletal pain, but their use is controversial as repeated exposures to corticosteroids can lead to deleterious effects on musculoskeletal tissue. Ozone injections have been proposed as a possible treatment for musculoskeletal pain; however, their effectiveness has not been compared with corticosteroids.
UNASSIGNED: To evaluate the effectiveness of ozone injections for reducing pain in individuals with musculoskeletal pain in comparison with corticosteroid injections through a meta-analysis.
UNASSIGNED: An online systematic search was performed using electronic databases up to September 2023. We searched for studies that compared corticosteroid injections with ozone injections in the treatment of musculoskeletal pain of diverse origins.
UNASSIGNED: Eleven studies were included comprising a total of 534 individuals. In the overall pooled analysis, a pain reduction in favor of corticosteroid injections was found in the short term (d= 0.31, 95% CI 0.01 to 0.60, p (z) 0.04, I2 = 32%). In the medium term, no significant differences were found in reducing pain between groups (d=-0.17, 95% CI -0.42 to 0.07, p (z) 0.15, I2 = 0%).
UNASSIGNED: Our results suggest that corticosteroids injections are more effective in reducing musculoskeletal pain in the short term, but equally effective in the medium term when compared with ozone injections. Nonetheless, better-quality clinical trials are necessary to corroborate these results.
UNASSIGNED: To evaluate the effectiveness of ozone injections for reducing pain in individuals with musculoskeletal pain in comparison with corticosteroid injections through a meta-analysis.
UNASSIGNED: An online systematic search was performed using electronic databases up to September 2023. We searched for studies that compared corticosteroid injections with ozone injections in the treatment of musculoskeletal pain of diverse origins.
UNASSIGNED: Eleven studies were included comprising a total of 534 individuals. In the overall pooled analysis, a pain reduction in favor of corticosteroid injections was found in the short term (d= 0.31, 95% CI 0.01 to 0.60, p (z) 0.04, I2 = 32%). In the medium term, no significant differences were found in reducing pain between groups (d=-0.17, 95% CI -0.42 to 0.07, p (z) 0.15, I2 = 0%).
UNASSIGNED: Our results suggest that corticosteroids injections are more effective in reducing musculoskeletal pain in the short term, but equally effective in the medium term when compared with ozone injections. Nonetheless, better-quality clinical trials are necessary to corroborate these results.
摘要：
背景：皮质类固醇注射剂经常用于肌肉骨骼疼痛的短期治疗，但是他们的使用是有争议的，因为反复暴露于皮质类固醇会导致对肌肉骨骼组织的有害影响。臭氧注射已被提议作为肌肉骨骼疼痛的可能治疗方法；然而，它们的有效性尚未与皮质类固醇相比。
目的：通过荟萃分析评估臭氧注射与皮质类固醇注射相比减轻肌肉骨骼疼痛个体疼痛的有效性。
方法：使用电子数据库进行了在线系统搜索，直到2023年9月。我们搜索了比较皮质类固醇注射与臭氧注射治疗不同起源的肌肉骨骼疼痛的研究。
结果：共纳入11项研究，共534人。在总体汇总分析中，发现短期内疼痛减轻有利于皮质类固醇注射(d=0.31,95%CI0.01~0.60,p(z)0.04,I2=32%).从中期来看,两组间在减轻疼痛方面无显著差异(d=-0.17,95%CI-0.42~0.07,p(z)0.15,I2=0%).
结论：我们的研究结果表明，短期注射皮质类固醇更有效地减轻肌肉骨骼疼痛，但与臭氧注射相比，在中期同样有效。尽管如此，有必要进行更高质量的临床试验来证实这些结果。
目的：通过荟萃分析评估臭氧注射与皮质类固醇注射相比减轻肌肉骨骼疼痛个体疼痛的有效性。
方法：使用电子数据库进行了在线系统搜索，直到2023年9月。我们搜索了比较皮质类固醇注射与臭氧注射治疗不同起源的肌肉骨骼疼痛的研究。
结果：共纳入11项研究，共534人。在总体汇总分析中，发现短期内疼痛减轻有利于皮质类固醇注射(d=0.31,95%CI0.01~0.60,p(z)0.04,I2=32%).从中期来看,两组间在减轻疼痛方面无显著差异(d=-0.17,95%CI-0.42~0.07,p(z)0.15,I2=0%).
结论：我们的研究结果表明，短期注射皮质类固醇更有效地减轻肌肉骨骼疼痛，但与臭氧注射相比，在中期同样有效。尽管如此，有必要进行更高质量的临床试验来证实这些结果。
