PDF(Pubmed)
Abstract：
Primary intracranial malignant melanoma (PIMM) represents 0.07% of central nervous system tumours; clinical behaviour and prognosis are not well documented. Preoperative diagnosis of PIMM is complex and it could be easily misdiagnosed, especially with malignant meningioma.We are reporting a case of a man with a history of rapidly arising motor slowing associated with urinary incontinence, presenting with mild convergent strabismus caused by paralysis in abduction in the right eye. A brain CT showed a lesion compatible with malignant spheno-orbital meningioma, and the patient underwent gross total resection. Intraoperatively, the blackish lesion infiltrated and eroded the bone; it was placed externally on the dura mater with a mild reaction and without attachment. Histological examination confirmed PIMM.Intraosseous localisation of PIMM has been observed in the basic bone structure of the oral cavity. We report the first intraosseous spheno-orbital PIMM case and present an embryological theory about how this unusual tumour can develop.
摘要：
原发性颅内恶性黑色素瘤（PIMM）占中枢神经系统肿瘤的0.07％；临床行为和预后没有很好的记录。PIMM术前诊断复杂,易误诊,尤其是恶性脑膜瘤.我们正在报告一个病例，该病例有与尿失禁相关的快速出现运动减慢的病史，表现为右眼外展瘫痪引起的轻度会聚性斜视。脑部CT显示病变与恶性蝶眶脑膜瘤相符，患者接受了大体全切除。术中,黑色病变浸润并侵蚀了骨骼；它被放置在硬脑膜上，反应轻微，没有附着。组织学检查证实PIMM。已在口腔的基本骨结构中观察到PIMM的骨内定位。我们报告了第一例骨内蝶眶PIMM病例，并提出了有关这种异常肿瘤如何发展的胚胎学理论。
