{Reference Type}: Case Reports
{Title}: Unusual case of intraosseous primary intracranial malignant melanoma.
{Author}: Guarrera B;Coati I;Giarletta M;
{Journal}: BMJ Case Rep
{Volume}: 17
{Issue}: 1
{Year}: 2024 Jan 25
暂无{DOI}: 10.1136/bcr-2023-256623
{Abstract}: Primary intracranial malignant melanoma (PIMM) represents 0.07% of central nervous system tumours; clinical behaviour and prognosis are not well documented. Preoperative diagnosis of PIMM is complex and it could be easily misdiagnosed, especially with malignant meningioma.We are reporting a case of a man with a history of rapidly arising motor slowing associated with urinary incontinence, presenting with mild convergent strabismus caused by paralysis in abduction in the right eye. A brain CT showed a lesion compatible with malignant spheno-orbital meningioma, and the patient underwent gross total resection. Intraoperatively, the blackish lesion infiltrated and eroded the bone; it was placed externally on the dura mater with a mild reaction and without attachment. Histological examination confirmed PIMM.Intraosseous localisation of PIMM has been observed in the basic bone structure of the oral cavity. We report the first intraosseous spheno-orbital PIMM case and present an embryological theory about how this unusual tumour can develop.