PDF(Pubmed)
Abstract：
BACKGROUND: Assisted Reproductive Technology utilizes human sperm, eggs, or embryos in vitro to produce pregnancy. However, there is no evidence of the acceptance of these technologies by the community.
OBJECTIVE: This study aimed to determine the pooled prevalence of positive attitudes toward the acceptance of donor eggs, embryos, and sperm.
METHODS: The protocol was registered in PROSPERO (number: CRD42022348036). The Condition, Context and Population (CoCoPop) protocol of the systematic review was used to address the relevant questions regarding the objective of the study. Data were extracted into Excel and pooled estimates were calculated using STATA Version 16.
RESULTS: The pooled prevalence of positive attitudes toward accepting donor eggs, embryos, and sperms was 38.63%, 33.20%, and 31.34%, respectively. Subgroup analysis revealed that the pooled prevalence of positive attitudes toward accepting donor eggs was high in non-Asian countries (47.78%) and among infertile men (38.60%). Similarly, the pooled prevalence of positive attitudes toward accepting donor eggs was high in non-Asian countries (47.78%) and among infertile men (28.67%). However, the pooled prevalence of positive attitudes toward accepting donor sperm was high in non-Asian countries (37.6%) and among infertile women (28.19%).
CONCLUSIONS: The pooled estimate of the prevalence of positive attitudes toward accepting donor eggs was higher than the prevalence of positive attitudes toward accepting donor embryos and sperm. Infertile men and non-Asian countries have a higher prevalence of positive attitudes toward accepting eggs and embryos, whereas non-Asian countries and infertile women present a higher prevalence of positive attitudes toward accepting donor sperm. Therefore, regulatory bodies and policymakers should modify their rules and regulations to ensure the availability of minimum standards for the ethical and safe practice of donor conception as a treatment for infertility at national and international levels.
Assisted Reproductive Technology (ART) utilizes human sperm, eggs, or embryos in vitro to induce pregnancy; however, there is no evidence of community acceptance of these technologies. A systematic review and meta-analysis found that 38.63% of infertile couples had positive attitudes toward donor eggs, while 33.20% and 31.34% had negative attitudes. Females are more amenable to accepting donor gametes, embryos, or eggs than males, and females are more amenable to accepting donor eggs than donor sperm. To improve attitudes toward donor conception, infertile couples must understand the medical and obstetric risks associated with donor-assisted conception. This review recommends strengthening counseling for infertile couples and offering support to those with negative attitudes toward donor conception. Regulatory bodies and policymakers should consider the needs of infertile couples and modify their rules to ensure minimum standards for ethical and safe practices of donor conception as a treatment for infertility.
OBJECTIVE: This study aimed to determine the pooled prevalence of positive attitudes toward the acceptance of donor eggs, embryos, and sperm.
METHODS: The protocol was registered in PROSPERO (number: CRD42022348036). The Condition, Context and Population (CoCoPop) protocol of the systematic review was used to address the relevant questions regarding the objective of the study. Data were extracted into Excel and pooled estimates were calculated using STATA Version 16.
RESULTS: The pooled prevalence of positive attitudes toward accepting donor eggs, embryos, and sperms was 38.63%, 33.20%, and 31.34%, respectively. Subgroup analysis revealed that the pooled prevalence of positive attitudes toward accepting donor eggs was high in non-Asian countries (47.78%) and among infertile men (38.60%). Similarly, the pooled prevalence of positive attitudes toward accepting donor eggs was high in non-Asian countries (47.78%) and among infertile men (28.67%). However, the pooled prevalence of positive attitudes toward accepting donor sperm was high in non-Asian countries (37.6%) and among infertile women (28.19%).
CONCLUSIONS: The pooled estimate of the prevalence of positive attitudes toward accepting donor eggs was higher than the prevalence of positive attitudes toward accepting donor embryos and sperm. Infertile men and non-Asian countries have a higher prevalence of positive attitudes toward accepting eggs and embryos, whereas non-Asian countries and infertile women present a higher prevalence of positive attitudes toward accepting donor sperm. Therefore, regulatory bodies and policymakers should modify their rules and regulations to ensure the availability of minimum standards for the ethical and safe practice of donor conception as a treatment for infertility at national and international levels.
Assisted Reproductive Technology (ART) utilizes human sperm, eggs, or embryos in vitro to induce pregnancy; however, there is no evidence of community acceptance of these technologies. A systematic review and meta-analysis found that 38.63% of infertile couples had positive attitudes toward donor eggs, while 33.20% and 31.34% had negative attitudes. Females are more amenable to accepting donor gametes, embryos, or eggs than males, and females are more amenable to accepting donor eggs than donor sperm. To improve attitudes toward donor conception, infertile couples must understand the medical and obstetric risks associated with donor-assisted conception. This review recommends strengthening counseling for infertile couples and offering support to those with negative attitudes toward donor conception. Regulatory bodies and policymakers should consider the needs of infertile couples and modify their rules to ensure minimum standards for ethical and safe practices of donor conception as a treatment for infertility.
摘要：
背景：辅助生殖技术利用人类精子，鸡蛋,或体外胚胎来产生怀孕。然而,没有证据表明社区接受这些技术。
目的：本研究旨在确定对接受供体卵的积极态度的汇总患病率，胚胎,和精子。
方法：该方案在PROSPERO（编号：CRD42022348036）中注册。条件,系统评价的背景和人口（CoCoPop）方案用于解决有关研究目标的相关问题。将数据提取到Excel中，并使用STATA第16版计算汇总估计值。
结果：对接受供体卵子的积极态度的汇总患病率，胚胎,精子率为38.63%,33.20%,和31.34%，分别。亚组分析显示，在非亚洲国家（47.78％）和不育男性（38.60％）中，对接受供体卵的积极态度的汇总患病率很高。同样，在非亚洲国家(47.78%)和不育男性(28.67%)中,接受供体卵子的积极态度的总患病率较高.然而,在非亚洲国家(37.6%)和不育女性(28.19%)中,接受供体精子的积极态度的总患病率较高.
结论：对接受供体卵子的积极态度的患病率的汇总估计高于对接受供体胚胎和精子的积极态度的患病率。不育男性和非亚洲国家对接受卵子和胚胎的积极态度较高，而非亚洲国家和不育妇女对接受供体精子的积极态度较高。因此,监管机构和政策制定者应修改其规则和条例，以确保在国家和国际层面上为捐赠者受孕作为不孕症治疗的道德和安全实践提供最低标准。
辅助生殖技术（ART）利用人类精子，鸡蛋,或体外诱导怀孕的胚胎；然而，没有证据表明社区接受这些技术。一项系统评价和荟萃分析发现，38.63%的不育夫妇对供体卵子持积极态度，33.20%和31.34%有消极态度。雌性更愿意接受供体配子，胚胎,或卵比雄性，雌性比供体精子更愿意接受供体卵子。为了改善对捐赠者概念的态度，不育夫妇必须了解与供体辅助受孕相关的医学和产科风险。这篇评论建议加强对不育夫妇的咨询，并为那些对捐赠者受孕持消极态度的人提供支持。监管机构和政策制定者应考虑不育夫妇的需求，并修改其规则，以确保供体受孕作为不孕症治疗的道德和安全实践的最低标准。
目的：本研究旨在确定对接受供体卵的积极态度的汇总患病率，胚胎,和精子。
方法：该方案在PROSPERO（编号：CRD42022348036）中注册。条件,系统评价的背景和人口（CoCoPop）方案用于解决有关研究目标的相关问题。将数据提取到Excel中，并使用STATA第16版计算汇总估计值。
结果：对接受供体卵子的积极态度的汇总患病率，胚胎,精子率为38.63%,33.20%,和31.34%，分别。亚组分析显示，在非亚洲国家（47.78％）和不育男性（38.60％）中，对接受供体卵的积极态度的汇总患病率很高。同样，在非亚洲国家(47.78%)和不育男性(28.67%)中,接受供体卵子的积极态度的总患病率较高.然而,在非亚洲国家(37.6%)和不育女性(28.19%)中,接受供体精子的积极态度的总患病率较高.
结论：对接受供体卵子的积极态度的患病率的汇总估计高于对接受供体胚胎和精子的积极态度的患病率。不育男性和非亚洲国家对接受卵子和胚胎的积极态度较高，而非亚洲国家和不育妇女对接受供体精子的积极态度较高。因此,监管机构和政策制定者应修改其规则和条例，以确保在国家和国际层面上为捐赠者受孕作为不孕症治疗的道德和安全实践提供最低标准。
辅助生殖技术（ART）利用人类精子，鸡蛋,或体外诱导怀孕的胚胎；然而，没有证据表明社区接受这些技术。一项系统评价和荟萃分析发现，38.63%的不育夫妇对供体卵子持积极态度，33.20%和31.34%有消极态度。雌性更愿意接受供体配子，胚胎,或卵比雄性，雌性比供体精子更愿意接受供体卵子。为了改善对捐赠者概念的态度，不育夫妇必须了解与供体辅助受孕相关的医学和产科风险。这篇评论建议加强对不育夫妇的咨询，并为那些对捐赠者受孕持消极态度的人提供支持。监管机构和政策制定者应考虑不育夫妇的需求，并修改其规则，以确保供体受孕作为不孕症治疗的道德和安全实践的最低标准。
