Abstract：
UNASSIGNED: Long-term re-intervention after ultrasound-guided high intensity focused ultrasound (USgHIFU) ablation was reported, and the prediction of non-perfusion volume ratio (NPVR) in differently aged patients with uterine fibroids (UFs) was explored.
UNASSIGNED: Patients with UFs who underwent USgHIFU ablation from January 2012 to December 2019 were enrolled and divided into < 40-year-old and ≥ 40-year-old groups. Cox regression was used to analyze the influencing factors of re-intervention rate, and receiver operating characteristic (ROC) curve was used to analyze the correlation between NPVR and re-intervention rate.
UNASSIGNED: A total of 2141 patients were enrolled, and 1558 patients were successfully followed up. The 10-year cumulative re-intervention rate was 21.9%, and the < 40-year-old group had a significantly higher rate than the ≥ 40-year-old group (30.8% vs. 19.1%, p < 0.001). NPVR was an independent risk factor in both two groups. When the NPVR reached 80.5% in the < 40-year-old group and 75.5% in the ≥ 40-year-old group, the risk of long-term re-intervention was satisfactory.
UNASSIGNED: The long-term outcome of USgHIFU is promising. The re-intervention rate is related to NPVR in differently aged patients. Young patients need a high NPVR to reduce re-intervention risk.
UNASSIGNED: Patients with UFs who underwent USgHIFU ablation from January 2012 to December 2019 were enrolled and divided into < 40-year-old and ≥ 40-year-old groups. Cox regression was used to analyze the influencing factors of re-intervention rate, and receiver operating characteristic (ROC) curve was used to analyze the correlation between NPVR and re-intervention rate.
UNASSIGNED: A total of 2141 patients were enrolled, and 1558 patients were successfully followed up. The 10-year cumulative re-intervention rate was 21.9%, and the < 40-year-old group had a significantly higher rate than the ≥ 40-year-old group (30.8% vs. 19.1%, p < 0.001). NPVR was an independent risk factor in both two groups. When the NPVR reached 80.5% in the < 40-year-old group and 75.5% in the ≥ 40-year-old group, the risk of long-term re-intervention was satisfactory.
UNASSIGNED: The long-term outcome of USgHIFU is promising. The re-intervention rate is related to NPVR in differently aged patients. Young patients need a high NPVR to reduce re-intervention risk.
摘要：
■报告了超声引导高强度聚焦超声（USgHIFU）消融后的长期再介入，探讨非灌注容积比(NPVR)在不同年龄子宫肌瘤(UFs)患者中的预测价值。
■纳入2012年1月至2019年12月接受USgHIFU消融的UF患者，并分为<40岁和≥40岁组。采用Cox回归分析再干预率的影响因素,采用受试者工作特征(ROC)曲线分析NPVR与再干预率的相关性。
■共纳入2141名患者，1558例患者成功随访。10年累计再干预率为21.9%,<40岁组的发病率明显高于≥40岁组(30.8%vs.19.1%,p<0.001)。NPVR是两组的独立危险因素。当NPVR在<40岁组中达到80.5%,在≥40岁组中达到75.5%时,长期再干预的风险令人满意.
■USgHIFU的长期结果是有希望的。不同年龄患者的再干预率与NPVR相关。年轻患者需要高NPVR以降低再次干预风险。
■纳入2012年1月至2019年12月接受USgHIFU消融的UF患者，并分为<40岁和≥40岁组。采用Cox回归分析再干预率的影响因素,采用受试者工作特征(ROC)曲线分析NPVR与再干预率的相关性。
■共纳入2141名患者，1558例患者成功随访。10年累计再干预率为21.9%,<40岁组的发病率明显高于≥40岁组(30.8%vs.19.1%,p<0.001)。NPVR是两组的独立危险因素。当NPVR在<40岁组中达到80.5%,在≥40岁组中达到75.5%时,长期再干预的风险令人满意.
■USgHIFU的长期结果是有希望的。不同年龄患者的再干预率与NPVR相关。年轻患者需要高NPVR以降低再次干预风险。
