{Reference Type}: Journal Article
{Title}: Long-term re-intervention after USgHIFU and prediction of NPVR in different ages of patients with uterine fibroids.
{Author}: Li S;Ma WW;Yang MJ;Deng YB;Hu L;Chen JY;
{Journal}: Int J Hyperthermia
{Volume}: 41
{Issue}: 1
{Year}: 2024
{Factor}: 3.753
{DOI}: 10.1080/02656736.2024.2304264
{Abstract}: <B>UNASSIGNED: </B>Long-term re-intervention after ultrasound-guided high intensity focused ultrasound (USgHIFU) ablation was reported, and the prediction of non-perfusion volume ratio (NPVR) in differently aged patients with uterine fibroids (UFs) was explored.<BR><B>UNASSIGNED: </B>Patients with UFs who underwent USgHIFU ablation from January 2012 to December 2019 were enrolled and divided into < 40-year-old and ≥ 40-year-old groups. Cox regression was used to analyze the influencing factors of re-intervention rate, and receiver operating characteristic (ROC) curve was used to analyze the correlation between NPVR and re-intervention rate.<BR><B>UNASSIGNED: </B>A total of 2141 patients were enrolled, and 1558 patients were successfully followed up. The 10-year cumulative re-intervention rate was 21.9%, and the < 40-year-old group had a significantly higher rate than the ≥ 40-year-old group (30.8% vs. 19.1%, p < 0.001). NPVR was an independent risk factor in both two groups. When the NPVR reached 80.5% in the < 40-year-old group and 75.5% in the ≥ 40-year-old group, the risk of long-term re-intervention was satisfactory.<BR><B>UNASSIGNED: </B>The long-term outcome of USgHIFU is promising. The re-intervention rate is related to NPVR in differently aged patients. Young patients need a high NPVR to reduce re-intervention risk.