关键词: Antibiotic susceptibility Salmonella species Salmonella endophthalmitis endogenous endophthalmitis endophthalmitis in immunocompetent endophthalmitis with retinopathy of prematurity

Mesh : Adult Infant, Newborn Humans Typhoid Fever / drug therapy Retrospective Studies Anti-Bacterial Agents / therapeutic use Endophthalmitis / diagnosis Salmonella Eye Infections, Bacterial / microbiology

来  源:   DOI:10.1080/08820538.2024.2308802

Abstract:
UNASSIGNED: To report two rare cases of Salmonella endogenous endophthalmitis in an immunocompromised premature baby and an immunocompetent adult and do a brief literature review of related cases. Diagnosis in both cases was confirmed only after the pathogen grew from ocular samples, in the absence of clear signs of enteric fever.
UNASSIGNED: Retrospective analysis of medical and microbiology records.
UNASSIGNED: Both of our cases of Salmonella endophthalmitis had poor visual outcome, despite timely and aggressive management and irrespective of immune status of the patient. Salmonella infection being a rare cause of endophthalmitis was not initially suspected as the adult had minimal systemic symptoms 2 weeks before presentation, while the preterm baby was still on milk feeds. These were just two microbiologically confirmed cases of Salmonella endophthalmitis at our institute over the past 10 years, though enteric fever due to Salmonella species is endemic in Asian countries.
UNASSIGNED: Salmonella endophthalmitis, though rare, leads to poor visual outcomes despite early recognition and aggressive management and may be confused with other infections or non-infectious entities such as necrotizing retinoblastoma in babies, in the absence of clear systemic signs of the disease.
摘要:
报告1例免疫功能低下的早产儿和1例免疫功能正常的成年人中2例沙门氏菌内源性眼内炎的罕见病例,并对相关病例进行简要文献复习。只有在病原体从眼部样本中生长出来后,才确认了这两种情况下的诊断。在没有明显的肠道发热迹象的情况下。
医学和微生物学记录的回顾性分析。
我们的两例沙门氏菌眼内炎的视力都不好,尽管及时积极的管理,无论患者的免疫状态如何。最初没有怀疑沙门氏菌感染是眼内炎的罕见原因,因为成年人在出现前2周有轻微的全身症状。而早产儿仍在吃牛奶。在过去的10年中,这只是我们研究所的两例沙门氏菌眼内炎的微生物学确诊病例,尽管沙门氏菌引起的肠热在亚洲国家是地方性的。
沙门氏菌眼内炎,虽然罕见,尽管早期识别和积极管理,但仍导致不良的视觉结果,并且可能与其他感染或非感染性实体(如婴儿坏死性视网膜母细胞瘤)相混淆,在没有明确的全身性疾病体征的情况下。
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