PDF(Pubmed)
Abstract：
UNASSIGNED: To evaluate the outcomes of surgical intervention in eyes with neovascular glaucoma (NVG) and poor vision, comparing the Ahmed glaucoma implant with cyclophotocoagulation (CPC).
UNASSIGNED: This study is a double-armed cohort retrospective review of medical records of patients with NVG who had a visual acuity of 20/200 or less and underwent one of the two procedures as a primary intervention: Ahmed glaucoma valve (AGV) or cyclophotocoagulation (CPC). The study was conducted at King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia, from January 2014 to June 2019, with a total study period of 1 year. The main outcome measures included the surgical success rate, changes in intraocular pressure (IOP), the number of antiglaucoma medications, corrected distance visual acuity, and the reoperation rate for glaucoma.
UNASSIGNED: The preoperative IOP was 40.4 ± 10.6 mmHg (Median 40) in the CPC group and 39.4 ± 10.2 mmHg (Median 40) in the AGV group (P = 0.6). At 1 year, the IOP ranged from 12.5 to 28 mmHg (Median 18) in the CPC group and 14 to 21.5 mmHg (Median 17) in the AGV group (P = 0.016). Survival analysis showed a 51% success rate in the CPC group and an 89% success rate at 1 year in the AGV group (p>0.0001).
UNASSIGNED: CPC and AGV procedures yielded good outcomes with similar IOP levels 12 months after the surgery. However, AGV demonstrated a higher overall success rate and a lower medication requirement than CPC.
UNASSIGNED: This study is a double-armed cohort retrospective review of medical records of patients with NVG who had a visual acuity of 20/200 or less and underwent one of the two procedures as a primary intervention: Ahmed glaucoma valve (AGV) or cyclophotocoagulation (CPC). The study was conducted at King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia, from January 2014 to June 2019, with a total study period of 1 year. The main outcome measures included the surgical success rate, changes in intraocular pressure (IOP), the number of antiglaucoma medications, corrected distance visual acuity, and the reoperation rate for glaucoma.
UNASSIGNED: The preoperative IOP was 40.4 ± 10.6 mmHg (Median 40) in the CPC group and 39.4 ± 10.2 mmHg (Median 40) in the AGV group (P = 0.6). At 1 year, the IOP ranged from 12.5 to 28 mmHg (Median 18) in the CPC group and 14 to 21.5 mmHg (Median 17) in the AGV group (P = 0.016). Survival analysis showed a 51% success rate in the CPC group and an 89% success rate at 1 year in the AGV group (p>0.0001).
UNASSIGNED: CPC and AGV procedures yielded good outcomes with similar IOP levels 12 months after the surgery. However, AGV demonstrated a higher overall success rate and a lower medication requirement than CPC.
摘要：
■为了评估新生血管性青光眼（NVG）和视力不佳的眼的手术干预效果，比较Ahmed青光眼植入物与睫状体光凝（CPC）。
■本研究是对NVG患者的医疗记录的双臂队列回顾性研究，这些患者的视力为20/200或更低，并接受了两种手术之一作为主要干预措施：Ahmed青光眼阀（AGV）或睫状体光凝（CPC）。这项研究是在利雅得的哈立德国王眼科专科医院进行的，沙特阿拉伯,2014年1月至2019年6月，总研究期为1年。主要结局指标包括手术成功率，眼内压（IOP）的变化，抗青光眼药物的数量，远距矫正视力,青光眼的再手术率。
■CPC组术前眼压为40.4±10.6mmHg（中位数40），AGV组为39.4±10.2mmHg（中位数40）（P=0.6）。在1年,CPC组的IOP为12.5~28mmHg(中位数18),AGV组的IOP为14~21.5mmHg(中位数17)(P=0.016).生存分析显示,CPC组成功率为51%,AGV组1年成功率为89%(p>0.0001)。
CPC和AGV手术在手术后12个月取得了良好的结果，IOP水平相似。然而,与CPC相比，AGV显示出更高的总体成功率和更低的药物需求。
■本研究是对NVG患者的医疗记录的双臂队列回顾性研究，这些患者的视力为20/200或更低，并接受了两种手术之一作为主要干预措施：Ahmed青光眼阀（AGV）或睫状体光凝（CPC）。这项研究是在利雅得的哈立德国王眼科专科医院进行的，沙特阿拉伯,2014年1月至2019年6月，总研究期为1年。主要结局指标包括手术成功率，眼内压（IOP）的变化，抗青光眼药物的数量，远距矫正视力,青光眼的再手术率。
■CPC组术前眼压为40.4±10.6mmHg（中位数40），AGV组为39.4±10.2mmHg（中位数40）（P=0.6）。在1年,CPC组的IOP为12.5~28mmHg(中位数18),AGV组的IOP为14~21.5mmHg(中位数17)(P=0.016).生存分析显示,CPC组成功率为51%,AGV组1年成功率为89%(p>0.0001)。
CPC和AGV手术在手术后12个月取得了良好的结果，IOP水平相似。然而,与CPC相比，AGV显示出更高的总体成功率和更低的药物需求。
