Abstract:
OBJECTIVE: Melanoma is the leading cause of death from skin cancer in the world. Despite the advances in molecular diagnosis, the differential diagnosis between melanoma and benign melanocytic tumors relies on histopathology. However, not all of the criteria for the microscopy of a biopsy of a melanocytic tumor are applicable to all locations.
METHODS: We highlight these difficulties in the presentation of 2cases of melanocytic tumors in unusual locations which were diagnostically challenging.
RESULTS: After analyzing the relevant literature, the atypical histopathological characteristics of melanocytic tumors could be specified for unusual anatomical sites.
摘要:
目的:黑色素瘤是世界上皮肤癌死亡的主要原因。尽管分子诊断取得了进展,黑素瘤和良性黑素细胞肿瘤的鉴别诊断依赖于组织病理学。然而,并非所有黑素细胞肿瘤活检的显微镜检查标准都适用于所有部位.
方法:我们强调了2例黑素细胞肿瘤在异常位置的表现中的这些困难,这在诊断上是有挑战性的。
结果:在分析相关文献后,黑素细胞肿瘤的不典型组织病理学特征可用于异常解剖部位.