PDF(Pubmed)
Abstract：
UNASSIGNED: The study aimed to analyze the three-dimensional characteristics of nystagmus induced by different semicircular canal combinations in healthy young people, and to determine the reference range of nystagmus slow phase velocity (SPV) and its asymmetry.
UNASSIGNED: Fifty-two healthy volunteers (26 males and 26 females, aged 17-42 years, average 23.52 ± 6.59), were recruited to perform the manual triaxial rotation testing with a 3D-Videonystagmography (3D-VNG) device (VertiGoggles (ZT-VNG-II), Shanghai ZEHNIT Medical Technology Co., Ltd., Shanghai, China) using a 0.3 Hz prompt beat and a 90° amplitude, respectively. The induced nystagmus around the Z-, X-, and Y-axes were recorded in the yaw, pitch, and roll planes. The directions and slow phase velocities of the horizontal, vertical, and torsional components of the induced nystagmus under different semicircular canal combinations (the left lateral and right lateral semicircular canal combination, bilateral anterior semicircular canals, bilateral posterior semicircular canals combination, and the anterior and posterior semicircular canals combination of each ear), as well as their asymmetry, were taken as the observation indexes to analyze the characteristics of the nystagmus vectors of different combinations.
UNASSIGNED: Fifty-two healthy volunteers had no spontaneous nystagmus. The characteristic nystagmus was induced by the same head movement direction in all three axial rotation tests. The SPVs of the left and right nystagmus were 44.45 ± 15.75°/s and 43.79 ± 5.42°/s, respectively, when the subjects\' heads were turned left or right around the Z-axis (yaw). The SPVs of vertically upward and downward nystagmus were 31.67 ± 9.46°/s and 30.01 ± 9.20°/s, respectively, when the subjects\' heads were pitched around the X-axis (pitch). The SPVs of torsional nystagmus, with the upper poles of the eyes twisting slowly to the right and left ears (from the participant\'s perspective), were 28.99 ± 9.20°/s and 28.35 ± 8.17°/s, respectively, when the subjects\' heads were turned left or right around the Y-axis (roll). There was no significant difference in the SPVs of nystagmus induced by the same rotation axis in two opposite directions (p > 0.05). The reference ranges for the slow phase velocities (SPVs) of nystagmus induced by the triaxial rotation testing were as follows: For the Z-axis (yaw), the SPVs were 13.58-75.32°/s for leftward head rotation and 13.56-74.02°/s for rightward head rotation. For the X-axis (pitch), the SPVs were 13.13-50.21°/s for upward head nystagmus and 11.98-48.04°/s for downward head nystagmus. For the Y-axis (roll), the SPVs were 10.97-47.02°/s for the left-sided head rotation and 12.34-44.35°/s for the right-sided head rotation.
UNASSIGNED: This study clarified the three-dimensional characteristics of nystagmus induced by different semicircular canal combinations in healthy young people. It also established a preliminary reference range of SPVs and SPV asymmetry of nystagmus induced by the vertical semicircular canal. It can further provide a basis for the mechanism of semicircular canal-induced nystagmus and the traceability of nystagmus in patients with otogenic vertigo. It is shown that the portable 3D-VNG eye mask can be used for the manual triaxial rotation testing to achieve the evaluation of the low-frequency angular vestibulo-ocular reflex (aVOR) function of the vertical semicircular canal, which is convenient, efficient, and practical.
UNASSIGNED: Fifty-two healthy volunteers (26 males and 26 females, aged 17-42 years, average 23.52 ± 6.59), were recruited to perform the manual triaxial rotation testing with a 3D-Videonystagmography (3D-VNG) device (VertiGoggles (ZT-VNG-II), Shanghai ZEHNIT Medical Technology Co., Ltd., Shanghai, China) using a 0.3 Hz prompt beat and a 90° amplitude, respectively. The induced nystagmus around the Z-, X-, and Y-axes were recorded in the yaw, pitch, and roll planes. The directions and slow phase velocities of the horizontal, vertical, and torsional components of the induced nystagmus under different semicircular canal combinations (the left lateral and right lateral semicircular canal combination, bilateral anterior semicircular canals, bilateral posterior semicircular canals combination, and the anterior and posterior semicircular canals combination of each ear), as well as their asymmetry, were taken as the observation indexes to analyze the characteristics of the nystagmus vectors of different combinations.
UNASSIGNED: Fifty-two healthy volunteers had no spontaneous nystagmus. The characteristic nystagmus was induced by the same head movement direction in all three axial rotation tests. The SPVs of the left and right nystagmus were 44.45 ± 15.75°/s and 43.79 ± 5.42°/s, respectively, when the subjects\' heads were turned left or right around the Z-axis (yaw). The SPVs of vertically upward and downward nystagmus were 31.67 ± 9.46°/s and 30.01 ± 9.20°/s, respectively, when the subjects\' heads were pitched around the X-axis (pitch). The SPVs of torsional nystagmus, with the upper poles of the eyes twisting slowly to the right and left ears (from the participant\'s perspective), were 28.99 ± 9.20°/s and 28.35 ± 8.17°/s, respectively, when the subjects\' heads were turned left or right around the Y-axis (roll). There was no significant difference in the SPVs of nystagmus induced by the same rotation axis in two opposite directions (p > 0.05). The reference ranges for the slow phase velocities (SPVs) of nystagmus induced by the triaxial rotation testing were as follows: For the Z-axis (yaw), the SPVs were 13.58-75.32°/s for leftward head rotation and 13.56-74.02°/s for rightward head rotation. For the X-axis (pitch), the SPVs were 13.13-50.21°/s for upward head nystagmus and 11.98-48.04°/s for downward head nystagmus. For the Y-axis (roll), the SPVs were 10.97-47.02°/s for the left-sided head rotation and 12.34-44.35°/s for the right-sided head rotation.
UNASSIGNED: This study clarified the three-dimensional characteristics of nystagmus induced by different semicircular canal combinations in healthy young people. It also established a preliminary reference range of SPVs and SPV asymmetry of nystagmus induced by the vertical semicircular canal. It can further provide a basis for the mechanism of semicircular canal-induced nystagmus and the traceability of nystagmus in patients with otogenic vertigo. It is shown that the portable 3D-VNG eye mask can be used for the manual triaxial rotation testing to achieve the evaluation of the low-frequency angular vestibulo-ocular reflex (aVOR) function of the vertical semicircular canal, which is convenient, efficient, and practical.
摘要：
■该研究旨在分析健康年轻人不同半规管组合引起的眼球震颤的三维特征，并确定眼球震颤慢相速度（SPV）及其不对称性的参考范围。
■52名健康志愿者（26名男性和26名女性，17-42岁,平均23.52±6.59)，被招募使用3D视频眼震描记术（3D-VNG）设备（VertiGoggles（ZT-VNG-II）进行手动三轴旋转测试，上海Zehnit医疗科技有限公司Ltd.,上海,中国）使用0.3Hz的快速节拍和90°的振幅，分别。Z-周围诱发的眼球震颤，X-,Y轴记录在偏航中，螺距,滚动飞机。水平方向和慢相速度，垂直,和不同半规管组合下诱导的眼球震颤的扭转分量(左外侧和右外侧半规管组合，双侧前半规管，双侧后半规管组合，以及每只耳朵的前后半规管组合)，以及它们的不对称性，以不同组合的眼球震颤载体为观察指标,分析其特征。
■52名健康志愿者没有自发性眼球震颤。在所有三个轴向旋转测试中，相同的头部运动方向诱发了特征性眼球震颤。左右眼球震颤的SPV分别为44.45±15.75°/s和43.79±5.42°/s,分别,当受试者的头部绕Z轴(偏航)向左或向右转动时。垂直向上和向下眼球震颤的SPV分别为31.67±9.46°/s和30.01±9.20°/s，分别,当受试者的头部围绕X轴倾斜(俯仰)时。扭转性眼球震颤的SPV，眼睛的上两极慢慢地扭转到右耳和左耳（从参与者的角度来看），分别为28.99±9.20°/s和28.35±8.17°/s，分别,当受试者的头部绕Y轴(滚动)向左或向右转动时。相同旋转轴在两个相反方向上诱导的眼球震颤的SPV没有显着差异（p>0.05）。三轴旋转测试引起的眼球震颤慢相速度（SPV）的参考范围如下：对于Z轴（偏航），向左旋转的SPV为13.58-75.32°/s，向右旋转的SPV为13.56-74.02°/s。对于X轴（俯仰），头部向上眼球震颤的SPV为13.13-50.21°/s，头部向下眼球震颤的SPV为11.98-48.04°/s。对于Y轴（滚动），左侧头部旋转的SPV为10.97-47.02°/s，右侧头部旋转的SPV为12.34-44.35°/s。
■这项研究阐明了健康年轻人中不同半规管组合诱发的眼球震颤的三维特征。它还建立了由垂直半规管引起的眼球震颤的SPV和SPV不对称性的初步参考范围。可进一步为探讨半规管诱发眼震的机制和耳源性眩晕患者眼震的溯源提供依据。表明便携式3D-VNG眼罩可用于手动三轴旋转测试，以实现对垂直半规管的低频角前庭眼反射（aVOR）功能的评估，这很方便，高效,实用。
■52名健康志愿者（26名男性和26名女性，17-42岁,平均23.52±6.59)，被招募使用3D视频眼震描记术（3D-VNG）设备（VertiGoggles（ZT-VNG-II）进行手动三轴旋转测试，上海Zehnit医疗科技有限公司Ltd.,上海,中国）使用0.3Hz的快速节拍和90°的振幅，分别。Z-周围诱发的眼球震颤，X-,Y轴记录在偏航中，螺距,滚动飞机。水平方向和慢相速度，垂直,和不同半规管组合下诱导的眼球震颤的扭转分量(左外侧和右外侧半规管组合，双侧前半规管，双侧后半规管组合，以及每只耳朵的前后半规管组合)，以及它们的不对称性，以不同组合的眼球震颤载体为观察指标,分析其特征。
■52名健康志愿者没有自发性眼球震颤。在所有三个轴向旋转测试中，相同的头部运动方向诱发了特征性眼球震颤。左右眼球震颤的SPV分别为44.45±15.75°/s和43.79±5.42°/s,分别,当受试者的头部绕Z轴(偏航)向左或向右转动时。垂直向上和向下眼球震颤的SPV分别为31.67±9.46°/s和30.01±9.20°/s，分别,当受试者的头部围绕X轴倾斜(俯仰)时。扭转性眼球震颤的SPV，眼睛的上两极慢慢地扭转到右耳和左耳（从参与者的角度来看），分别为28.99±9.20°/s和28.35±8.17°/s，分别,当受试者的头部绕Y轴(滚动)向左或向右转动时。相同旋转轴在两个相反方向上诱导的眼球震颤的SPV没有显着差异（p>0.05）。三轴旋转测试引起的眼球震颤慢相速度（SPV）的参考范围如下：对于Z轴（偏航），向左旋转的SPV为13.58-75.32°/s，向右旋转的SPV为13.56-74.02°/s。对于X轴（俯仰），头部向上眼球震颤的SPV为13.13-50.21°/s，头部向下眼球震颤的SPV为11.98-48.04°/s。对于Y轴（滚动），左侧头部旋转的SPV为10.97-47.02°/s，右侧头部旋转的SPV为12.34-44.35°/s。
■这项研究阐明了健康年轻人中不同半规管组合诱发的眼球震颤的三维特征。它还建立了由垂直半规管引起的眼球震颤的SPV和SPV不对称性的初步参考范围。可进一步为探讨半规管诱发眼震的机制和耳源性眩晕患者眼震的溯源提供依据。表明便携式3D-VNG眼罩可用于手动三轴旋转测试，以实现对垂直半规管的低频角前庭眼反射（aVOR）功能的评估，这很方便，高效,实用。
