PDF(Pubmed)
Abstract：
Giant cell tumors of the spine have a high recurrence rate owing to their special anatomical site; hence, further treatment after recurrence is very challenging. Achieving effective tumor control and improving the long-term quality of life of the patients are the main treatment purposes to consider for recurrent giant cell tumors of the spine. A patient showing giant cell tumor recurrence of the thoracic spine after curettage received denosumab combined with precision radiotherapy, through which the tumor gained good control and the patient could regain normal functioning. A review of the relevant literature suggested that denosumab combined with radiotherapy is an effective new approach for the treatment of recurrent giant cell tumors of the spine.
摘要：
脊柱巨细胞瘤由于其特殊的解剖部位而具有很高的复发率；因此，复发后的进一步治疗非常具有挑战性。实现有效的肿瘤控制和提高患者的长期生活质量是复发性脊柱巨细胞瘤的主要治疗目的。1例胸椎巨细胞瘤刮宫术后复发患者接受了denosumab联合精确放疗,肿瘤得到了良好的控制，患者可以恢复正常功能。对相关文献的回顾表明，denosumab联合放射治疗是治疗复发性脊柱巨细胞瘤的有效新方法。
