Abstract：
OBJECTIVE: To investigate the effectiveness of different acupuncture and moxibustion therapies in improving cognitive function in patients with mild cognitive impairment (MCI) to determine the optimal approach. This study aims to provide insights into the treatment of MCI patients for future randomized controlled trials (RCTs) and clinical decision-making.
METHODS: RCT studies were retrieved from databases including PubMed, Embase, Cochrane Library, Web of Science, CNKI, WANFANG, VIP, and SinoMed. The Cochrane risk of bias tool was used to assess the risk of bias for eligible trials. Bayesian network meta-analysis was conducted using R4.2.3 software.
RESULTS: A total of 46 RCTs with 3641 participants were included. The network meta-analysis showed that acupoint pressing + cognitive training + auricular point sticking, massage + western medicine treatment, and electroacupuncture + western medicine treatment ranked first, second, and third in improving MMSE score, respectively. Acupoint pressing + cognitive training, cognitive training + scalp acupuncture, and cognitive training + moxibustion ranked first, second, and third in improving MoCA score, respectively.
CONCLUSIONS: This study showed that acupoint pressing alone or acupoint pressing + auricular point sticking may improve cognitive function in MCI patients and possibly be the most effective acupuncture interventions for the treatment of MCI.
METHODS: RCT studies were retrieved from databases including PubMed, Embase, Cochrane Library, Web of Science, CNKI, WANFANG, VIP, and SinoMed. The Cochrane risk of bias tool was used to assess the risk of bias for eligible trials. Bayesian network meta-analysis was conducted using R4.2.3 software.
RESULTS: A total of 46 RCTs with 3641 participants were included. The network meta-analysis showed that acupoint pressing + cognitive training + auricular point sticking, massage + western medicine treatment, and electroacupuncture + western medicine treatment ranked first, second, and third in improving MMSE score, respectively. Acupoint pressing + cognitive training, cognitive training + scalp acupuncture, and cognitive training + moxibustion ranked first, second, and third in improving MoCA score, respectively.
CONCLUSIONS: This study showed that acupoint pressing alone or acupoint pressing + auricular point sticking may improve cognitive function in MCI patients and possibly be the most effective acupuncture interventions for the treatment of MCI.
摘要：
目的：探讨不同针灸疗法改善轻度认知障碍（MCI）患者认知功能的效果，以确定最佳治疗方法。本研究旨在为未来的随机对照试验（RCT）和临床决策提供有关MCI患者治疗的见解。
方法：RCT研究从包括PubMed，Embase,科克伦图书馆,WebofScience,CNKI,万方,VIP,还有SinoMed.Cochrane偏倚风险工具用于评估合格试验的偏倚风险。采用R4.2.3软件进行贝叶斯网络Meta分析。
结果：共纳入46个RCTs，3641名参与者。网络荟萃分析显示,穴位按压+认知训练+耳穴贴压,按摩+西药治疗,电针+西药治疗排名第一，第二,第三是提高MMSE得分，分别。穴位按压+认知训练,认知训练+头针,认知训练+艾灸排名第一，第二,第三是提高MoCA得分，分别。
结论：本研究表明，单独穴位按压或穴位按压+耳穴贴压均可改善MCI患者的认知功能，可能是治疗MCI最有效的针刺干预措施。
方法：RCT研究从包括PubMed，Embase,科克伦图书馆,WebofScience,CNKI,万方,VIP,还有SinoMed.Cochrane偏倚风险工具用于评估合格试验的偏倚风险。采用R4.2.3软件进行贝叶斯网络Meta分析。
结果：共纳入46个RCTs，3641名参与者。网络荟萃分析显示,穴位按压+认知训练+耳穴贴压,按摩+西药治疗,电针+西药治疗排名第一，第二,第三是提高MMSE得分，分别。穴位按压+认知训练,认知训练+头针,认知训练+艾灸排名第一，第二,第三是提高MoCA得分，分别。
结论：本研究表明，单独穴位按压或穴位按压+耳穴贴压均可改善MCI患者的认知功能，可能是治疗MCI最有效的针刺干预措施。
