Abstract：
Helicobacter pylori, a gram-negative bacterium, has been identified as a major contributor to gastrointestinal diseases, ranging from gastritis and peptic ulcers to more severe complications such as gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. While pharmacological eradication therapies have been successful in managing H. pylori-associated diseases, the implications of this bacterium on surgical interventions remain a topic of ongoing research and clinical consideration. This comprehensive review aims to elucidate the intricate surgical implications of H. pylori infection. Recent data on the well-known relationship between and the development of gastroduodenal diseases, including peptic ulcers and gastric cancer, is analyzed. Concurrently, Helicobacter pylori infection may have a role in promoting colonic carcinogenesis and, more interestingly, it has also been linked to biliary tract cancers. The review highlights the evolving landscape of H. pylori management in the context of surgical interventions, accentuating the need for further research to delineate optimal strategies for preoperative screening, eradication therapies, and their impact on surgical outcomes and long-term patient prognosis. Comprehending the surgical ramifications of H. pylori infection remains crucial, emphasizing the significance of interdisciplinary approaches and ongoing research effort aimed at enhancing patient care.
摘要：
幽门螺杆菌,革兰氏阴性细菌,已被确定为胃肠道疾病的主要原因，从胃炎和消化性溃疡到更严重的并发症，如胃腺癌和粘膜相关淋巴组织（MALT）淋巴瘤。虽然药物根除疗法已成功控制幽门螺杆菌相关疾病，该细菌对外科手术的影响仍是正在进行的研究和临床考虑的主题。这篇综合综述旨在阐明幽门螺杆菌感染的复杂手术影响。有关胃十二指肠疾病与疾病发展之间众所周知的关系的最新数据，包括消化性溃疡和胃癌,被分析。同时,幽门螺杆菌感染可能具有促进结肠癌发生的作用,更有趣的是，它也与胆道癌有关。这篇综述强调了在手术干预的背景下幽门螺杆菌管理的不断发展。强调需要进一步研究来描述术前筛查的最佳策略，根除疗法，以及它们对手术结果和长期患者预后的影响。了解幽门螺杆菌感染的手术后果仍然至关重要，强调跨学科方法和正在进行的旨在加强患者护理的研究工作的重要性。
