Abstract：
This study established the simultaneous determination of the selected endocrine-disrupting compounds (EDCs) and pesticides in rock, soil, water, moss, and feces samples collected from the Antarctic region. The spray-assisted droplet formation-based liquid phase microextraction (SADF-LPME) coupled to GC-MS system was developed and validated for the screening and monitoring of 29 selected EDCs and pesticides. Binary solvent system, 1:1 (v/v) dichlormethane: 1,2-dichloroethane mixture was employed as an extraction solvent and sprayed onto sample or standard solutions using a straightforward and practical spray apparatus. The factors affecting the extraction process such as extraction solvent type and ratio, extraction solvent volume (spray repetition), vortexing period, and sample pH were properly optimized. Analytical figures of the merit of the method were recorded under the optimal extraction/chromatographic conditions. The LOD, LOQ, and enhancement factor were in the range of 1.0 to 6.6 ng/g, 3.2 to 22.1 ng/g, and 3.7 to 158.9, respectively. The method demonstrated a good linear working range for all the selected analytes with proper coefficients of determination. The usability and reliability of the microextraction strategy was confirmed using seawater, moss, and soil samples, and the %recoveries were within an acceptable range (> 70%) for all examined samples. The environmental samples collected from the Horseshoe and Faure Islands of the Antarctica region were analyzed to assess the potential pollution of EDCs and pesticides. This method has the potential to be employed for the analysis of EDCs in routine analytical laboratories and for controlling and screening the organic pollutant content of different environmental samples.
摘要：
这项研究建立了同时测定岩石中选定的内分泌干扰化合物（EDCs）和农药的方法，土壤,水,苔藓,和从南极地区收集的粪便样本。开发并验证了与GC-MS系统耦合的基于喷雾辅助液滴形成的液相微萃取（SADF-LPME），用于筛选和监测29种选定的EDC和农药。二元溶剂系统,使用1:1(v/v)二氯甲烷:1,2-二氯乙烷混合物作为萃取溶剂,并使用简单且实用的喷雾装置喷雾到样品或标准溶液上。提取溶剂种类和配比等影响提取工艺的因素,萃取溶剂体积（重复喷雾），涡旋期，和样品的pH进行了适当的优化。在最佳提取/色谱条件下记录了该方法的优点的分析图。LOD,LOQ,增强因子在1.0至6.6ng/g范围内，3.2至22.1ng/g，分别为3.7至158.9。该方法对所有选定的分析物都具有良好的线性工作范围，并具有适当的测定系数。使用海水证实了微提取策略的可用性和可靠性，苔藓,和土壤样本，所有检查样品的回收率在可接受的范围内(>70%)。分析了从南极洲马蹄和福雷群岛收集的环境样品，以评估EDC和农药的潜在污染。该方法有可能用于常规分析实验室中的EDC分析以及控制和筛选不同环境样品中的有机污染物含量。
