PDF(Pubmed)
Abstract：
To explore Helicobacter pylori (Hp) infection status and its relationship with lifestyle habits and dietary factors in patients with chronic atrophic gastritis. Six hundred thirty-eight patients with chronic atrophic gastritis, who were admitted to our hospital from March 2021 to April 2023, were selected for the study. All patients underwent the 13C urea breath test. The relationship between the detection rate of Hp infection and the clinical characteristics, lifestyle habits, and dietary factors of the patients was analyzed. Among the 638 patients with chronic atrophic gastritis, 531 patients were tested positive for Hp infection, the positive rate for Hp infection was approximately 83.23%. Analyzing the clinical characteristics of the patients, it was found that age, family history of gastric cancer, degree of chronic inflammation, degree of glandular atrophy, presence of low-grade dysplasia, and intestinal metaplasia all have an impact on the positive detection rate of patients (P < .05). Analyzing the patients\' lifestyle habits, it was found that BMI, smoking history, alcohol consumption, preference for spicy food, dining location, consumption of pickled foods, frequent consumption of grilled/barbecued foods, preference for strong tea, consumption of sweets, and work-related stress had an impact on the positive rate of Hp infection in patients (P < .05). The discovery showed that the levels of total protein, albumin, hemoglobin, cholesterol, and the intake of livestock and poultry meat, seafood, dairy products, vegetables, fruits, and fats have an impact on the positivity rate of Hp infection in patients (P < .05). A multiple logistic regression analysis was performed, and it was found that patients\' age, family history of gastric cancer, degree of chronic inflammation, degree of glandular atrophy, presence of low-grade dysplasia, presence of wasting or obesity, history of alcohol consumption, preference for spicy food, dining location, frequent consumption of strong tea, high work pressure, high intake of fish and seafood, low intake of dairy products, low intake of vegetables, low intake of fruits, and low intake of fats all had an impact on the occurrence of Hp infection in patients (P < .05). There is a certain correlation between patients\' lifestyle habits, dietary factors, and clinical characteristics with the occurrence of Hp infection. These factors can assist in the prevention of Hp infection.
摘要：
探讨慢性萎缩性胃炎患者幽门螺杆菌(Hp)感染状况及其与生活习惯和饮食因素的关系。六百三十八位慢性萎缩性胃炎病人,我们选择了2021年3月至2023年4月入住我们医院的患者进行研究.所有患者均接受13C尿素呼气试验。Hp感染检出率与临床特征的关系,生活习惯,并对患者的饮食因素进行分析。在638例慢性萎缩性胃炎患者中，531例患者Hp感染检测呈阳性，Hp感染阳性率约为83.23%。分析患者的临床特点,发现年龄，胃癌家族史,慢性炎症的程度，腺体萎缩程度,存在低度发育不良，肠上皮化生对患者的阳性检出率均有影响(P<0.05)。分析患者的生活习惯，发现BMI，吸烟史,酒精消费,喜欢辛辣的食物，用餐地点,食用腌制食品，经常食用烤/烧烤食品，偏爱浓茶，糖果的消费，工作压力对患者Hp感染阳性率有影响（P<0.05）。这一发现表明，总蛋白质的水平，白蛋白,血红蛋白,胆固醇,以及畜禽肉的摄入，海鲜,乳制品,蔬菜,水果,脂肪对患者Hp感染阳性率有影响(P<0.05)。进行了多元logistic回归分析，发现病人的年龄,胃癌家族史,慢性炎症的程度，腺体萎缩程度,存在低度发育不良，存在消瘦或肥胖，饮酒史,喜欢辛辣的食物，用餐地点,经常食用浓茶，工作压力大,鱼和海鲜的摄入量高，乳制品摄入量低，蔬菜摄入量低，水果摄入量低，低脂肪摄入均对患者Hp感染的发生有影响(P<0.05)。患者的生活习惯之间存在一定的相关性，饮食因素，临床特点与Hp感染的发生有关。这些因素可以帮助预防Hp感染。
