Abstract：
Plant secondary metabolites offer resistance to invasion by herbivorous organisms, and are also useful in the chemical, pharmaceutical, cosmetic, and fragrance industries. There are numerous approaches to enhancing secondary metabolite yields. However, a growing number of studies has indicated that feedback regulation may be critical in regulating secondary metabolite biosynthesis. Here, we review examples of feedback regulation in secondary metabolite biosynthesis pathways, phytohormone signal transduction, and complex deposition sites associated with secondary metabolite biosynthesis. We propose a new strategy to enhance secondary metabolite production based on plant feedback regulation. We also discuss challenges in feedback regulation that must be overcome before its application to enhancing secondary metabolite yields. This review discusses recent advances in the field and highlights a strategy to overcome feedback regulation-related obstacles and obtain high secondary metabolite yields.
摘要：
植物次生代谢产物对食草生物的入侵具有抵抗力，在化学中也很有用，Pharmaceutical,化妆品,和香料工业。有许多提高次生代谢物产量的方法。然而,越来越多的研究表明，反馈调节可能在调节次级代谢产物的生物合成中至关重要。这里,我们回顾了次级代谢物生物合成途径中反馈调节的例子，植物激素信号转导，和与次生代谢产物生物合成相关的复杂沉积位点。我们提出了一种基于植物反馈调节的提高次生代谢产物产量的新策略。我们还讨论了反馈调节方面的挑战，这些挑战在应用于提高次级代谢产物产量之前必须克服。这篇综述讨论了该领域的最新进展，并强调了克服反馈调节相关障碍并获得高次级代谢产物产量的策略。
