Pioneer 和 PRDM 转录因子协调二价表观遗传状态以保护细胞命运。
关键词: FOXA NuRD OCT4 PRC PRDM1 PRDM14 Polycomb repressive complex bivalent epigenetic state cell fate control complex nucleosome remodeling and deacetylation pioneer transcription factor
Mesh : Humans Transcription Factors / genetics metabolism Nucleosomes / genetics Cell Differentiation / genetics Polycomb-Group Proteins / metabolism Epigenesis, Genetic
来 源:
DOI:10.1016/j.molcel.2023.12.007
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