关键词: Biomarker Diabetes Frailty Handgrip strength Health Muscle Osteoporosis Sarcopenia Vital sign

Mesh : Humans Female Hand Strength Sarcopenia / diagnosis Diabetes Mellitus, Type 2 Quality of Life Biomarkers Vital Signs

来  源:   DOI:10.1186/s41043-024-00500-y   PDF(Pubmed)

Abstract:
Hand grip strength (HGS) serves as a fundamental metric in assessing muscle function and overall physical capability and is particularly relevant to the ageing population. HGS holds an important connection to the concept of sarcopenia, which encompasses the age-related decline in muscle mass, strength, and function. It has also been reported to indicate the health of an individual. We reviewed the interplay between HGS and various health parameters, including morbidity and mortality, by carrying out a literature search on PubMed, Scopus and Google Scholar between 10 and 30 August 2023, to identify the relevant papers on the relationship between health and HGS. We used several keywords like \'hand grip strength\', \'muscle strength, \'sarcopenia\', \'osteosarcopenia\', \'health biomarker\', \'osteoporosis\', and \'frailty\', to derive the appropriate literature for this review. This review has shown that the HGS can be measured reliably with a hand-held dynamometer. The cut-off values are different in various populations. It is lower in Asians, women, less educated and privileged, and those involved in sedentary work. Several diseases have shown a correlation with low HGS, e.g., Type 2 diabetes, cardiovascular disease, stroke, chronic kidney and liver disease, some cancers, sarcopenia and fragility fractures. The low HSG is also associated with increased hospitalization, nutritional status, overall mortality and quality of life. We believe that there is adequate evidence to show that HGS stands as an important biomarker of health. Its utility extends to the identification of diverse health issues and its potential as a new vital sign throughout the lifespan.
摘要:
手握力(HGS)是评估肌肉功能和整体身体能力的基本指标,尤其与人口老龄化相关。HGS与肌少症的概念有着重要的联系,包括与年龄相关的肌肉质量下降,力量,和功能。据报道,它也表明个人的健康状况。我们回顾了HGS和各种健康参数之间的相互作用,包括发病率和死亡率,通过在PubMed上进行文献检索,Scopus和GoogleScholar在2023年8月10日至30日之间,确定了有关健康与HGS之间关系的相关论文。我们使用了几个关键词,如“手握力”,肌肉力量,\'肌少症\',\'骨肉瘤\',\'健康生物标志物\',\'骨质疏松症\',和“脆弱”,为这篇综述得出适当的文献。这篇评论表明,可以使用手持式测功机可靠地测量HGS。截止值在各种群体中是不同的。它在亚洲人中较低,女人,受教育程度较低,享有特权,以及那些从事久坐工作的人。几种疾病显示出与低HGS相关,例如,2型糖尿病,心血管疾病,中风,慢性肾脏和肝脏疾病,一些癌症,肌肉减少症和脆性骨折。低HSG也与住院率增加有关,营养状况,总体死亡率和生活质量。我们相信有足够的证据表明HGS是健康的重要生物标志物。它的效用扩展到识别各种健康问题及其作为整个生命周期中的新生命体征的潜力。
公众号