关键词: Antiseptic-impregnated sutures Bacterial adherence Triclosan-coated sutures Wound healing.

Mesh : Humans Triclosan / pharmacology therapeutic use Polyglactin 910 Prospective Studies Anti-Bacterial Agents Sutures Anti-Infective Agents, Local / pharmacology therapeutic use Wound Healing Silk

来  源:   DOI:10.5005/jp-journals-10024-3553

Abstract:
OBJECTIVE: To assess the efficacy of antiseptic-coated silk sutures with triclosan-coated polyglactin 910 suture in reducing bacterial colonization after oral surgical procedures.
METHODS: The patients who required multiple sutures after surgical procedures in the mandible were the study subjects. The sites of suturing were divided into three groups. Group A - surgical site receiving black-braided silk suture (control group). Group B - surgical site receiving triclosan-coated Polyglactin 910 suture (experimental group). Group C - surgical site receiving antiseptic-coated silk suture (experimental group). Evaluation was done on the 3rd postoperative and 7th postoperative day. Microbial adherence was evaluated by microbiological study.
RESULTS: The mean comparison of microbial count between 3rd and 7th post-op day in the three groups shows an increased microbial colonization in the control group when compared with the experimental groups. The combined mean microbial adherence in the three groups showed microbial count in the uncoated silk suture (group A) as 10.35 ± 3.74, triclosan-coated suture (group B) as 6.28 ± 2.17 and iodoform + calendula oil-coated suture (group C) as 7.1 ± 2.02 which is statistically significant (p < 0.05).
CONCLUSIONS: The present research concluded that the pomade-coated silk suture is as efficient as triclosan-coated VICRYL PLUS Polyglactin 910 sutures in reducing the bacterial colonization in intraoral wound healing.
CONCLUSIONS: The pomade (iodoform + calendula oil) may be advocated in the field of oral and maxillofacial surgery for impregnating the suture materials which act as an antiseptic agent and a promoter of wound healing which is easily accessible and also cost-effective.
摘要:
目的:评估防腐涂层丝线与三氯生涂层聚乳酸肌动蛋白910缝线在口腔外科手术后减少细菌定植的功效。
方法:下颌骨外科手术后需要多次缝合的患者为研究对象。缝合部位分为三组。A组-手术部位接受黑色编织丝线缝合(对照组)。B组-接受三氯生涂层Polyglactin910缝合的手术部位(实验组)。C组-手术部位接受防腐涂层丝线(实验组)。在术后第3天和术后第7天进行评估。通过微生物学研究评估微生物的粘附性。
结果:三组术后第3天和第7天之间的微生物计数的平均比较显示,与实验组相比,对照组中的微生物定植增加。三组中的组合平均微生物粘附性显示未涂覆的丝线(A组)中的微生物计数为10.35±3.74,三氯生涂覆的丝线(B组)为6.28±2.17,碘仿+金盏花油涂覆的丝线(C组)中的微生物计数为7.1±2.02,这具有统计学意义(p<0.05)。
结论:本研究得出结论,在减少口腔内伤口愈合中的细菌定植方面,润发丝涂层缝合线与三氯生涂层VICRYLPLUSPolyGlactin910缝合线一样有效。
结论:在口腔颌面外科领域中,可以提倡润发(碘仿+金盏花油)用于浸渍缝合线材料,该材料可作为防腐剂和促进伤口愈合的促进剂,易于获得且具有成本效益。
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