Abstract：
We report a case of Toxoplasma gondii ( T. gondii ) antibody seronegativity in a 14-year-old boy with a primary infection of T. gondii after allogeneic hematopoietic stem cell transplantation for acute T-cell lymphoblastic leukemia who was rapidly diagnosed through metagenomic next-generation sequencing of peripheral blood as well as clinical manifestations. He was successfully cured with timely administration of trimethoprim-sulfamethoxazole due to early diagnosis.
摘要：
我们报告一例弓形虫（T。gondii）在异基因造血干细胞移植治疗急性T细胞淋巴细胞白血病后，一名14岁男孩初次感染弓形虫的抗体血清阴性，该男孩通过宏基因组下一代外周血测序以及临床表现迅速诊断。由于早期诊断，及时服用甲氧苄啶-磺胺甲恶唑成功治愈。
