关键词: oral cavity perineural tumor schwann cells schwannoma soft palate

来  源:   DOI:10.7759/cureus.50172   PDF(Pubmed)

Abstract:
Schwannomas are relatively slow-growing benign tumors of the nerve sheath. Approximately 25-40% of schwannomas occur in the head and neck region. However, schwannomas that present in the oral cavity are relatively rare, constituting around 1% of all described cases in the head and neck region. We report a case of a 20-year-old female who was found to have an intraoral palatal schwannoma. The patient presented with a painless swelling located on the right side of the soft palate. Investigations and management were commenced, and a computed tomography (CT) scan with contrast was done, which revealed cystic changes in a large soft palate mass lesion with a heterogeneous enhancement. The mass was surgically excised and sent for histopathological examination. The diagnosis of schwannoma was made due to the presence of the characteristic Antoni A and Antoni B areas. The immunohistochemical study done was positive for protein S-100. The postoperative follow-up went uneventful.
摘要:
神经鞘瘤是生长相对缓慢的神经鞘良性肿瘤。大约25-40%的神经鞘瘤发生在头颈部。然而,口腔中存在的神经鞘瘤相对罕见,约占头颈部所有描述病例的1%。我们报告了一例20岁的女性,该女性被发现患有口内pal神经鞘瘤。患者出现位于软腭右侧的无痛肿胀。调查和管理已经开始,并进行了对比计算机断层扫描(CT)扫描,揭示了一个大的软腭肿块病变的囊性改变,并伴有异质性增强。手术切除肿块并送去组织病理学检查。神经鞘瘤的诊断是由于特征性的安东尼A和安东尼B区域的存在。进行的免疫组织化学研究对蛋白S-100呈阳性。术后随访顺利。
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