PDF(Pubmed)
Abstract：
There is a growing body of recent literature linking the association of specific or multiple lifestyles with cognitive impairment, but most of these studies have been conducted in Western populations, and it is necessary to study multiple lifestyles and cognitive abilities in different populations, with the primary population of this study being a select group of community-dwelling older adults in Shanghai, China.
The sample included 2,390 community-dwelling Chinese participants. Their cognitive function was assessed using the Mini-Mental State Examination (MMSE). We defined a healthy lifestyle score on the basis of being non-smoking, performing ≥210 min/wk moderate/vigorous-intensity physical activity, having light to moderate alcohol consumption, eating vegetables and fruits daily, having a body mass index (BMI) of 18.5-23.9 kg/m2, and having a waist-to-hip ratio (WHR) <0.90 for men and <0.85 for women, for an overall score ranging from 0 to 6.
Compared with participants with ≤2 healthy lifestyle factors, the adjusted odds ratio (OR) and 95% confidence interval (CI) for participants with 4, 5, and 6 healthy lifestyle factors were 0.53 (95% CI, 0.29-0.98), 0.40 (95% CI, 0.21-0.75), and 0.36 (95% CI, 0.16-0.79), respectively. Only WHR (OR = 0.54, 95% CI = 0.37-0.78) and physical activity (OR = 0.69, 95% CI = 0.51-0.92) were associated with cognitive impairment. A healthy lifestyle correlated with overall cognition (β = 0.066, orientation (β = 0.049), language ability (β = 0.060), delayed recall (β = 0.045) and executive function (β = 0.044) (P all < 0.05).
The study provides evidence on an inverse association between healthy lifestyles and cognitive impairment. We investigated whether healthy lifestyle was related to specific cognitive functions to provide a theoretical basis for accurate clinical prescription.
The sample included 2,390 community-dwelling Chinese participants. Their cognitive function was assessed using the Mini-Mental State Examination (MMSE). We defined a healthy lifestyle score on the basis of being non-smoking, performing ≥210 min/wk moderate/vigorous-intensity physical activity, having light to moderate alcohol consumption, eating vegetables and fruits daily, having a body mass index (BMI) of 18.5-23.9 kg/m2, and having a waist-to-hip ratio (WHR) <0.90 for men and <0.85 for women, for an overall score ranging from 0 to 6.
Compared with participants with ≤2 healthy lifestyle factors, the adjusted odds ratio (OR) and 95% confidence interval (CI) for participants with 4, 5, and 6 healthy lifestyle factors were 0.53 (95% CI, 0.29-0.98), 0.40 (95% CI, 0.21-0.75), and 0.36 (95% CI, 0.16-0.79), respectively. Only WHR (OR = 0.54, 95% CI = 0.37-0.78) and physical activity (OR = 0.69, 95% CI = 0.51-0.92) were associated with cognitive impairment. A healthy lifestyle correlated with overall cognition (β = 0.066, orientation (β = 0.049), language ability (β = 0.060), delayed recall (β = 0.045) and executive function (β = 0.044) (P all < 0.05).
The study provides evidence on an inverse association between healthy lifestyles and cognitive impairment. We investigated whether healthy lifestyle was related to specific cognitive functions to provide a theoretical basis for accurate clinical prescription.
摘要：
■最近有越来越多的文献将特定或多种生活方式与认知障碍联系起来，但是这些研究大多是在西方人群中进行的，有必要研究不同人群的多种生活方式和认知能力，本研究的主要人群是上海社区居住的老年人群，中国。
■样本包括2390名社区居住的中国参与者。使用迷你精神状态检查（MMSE）评估他们的认知功能。我们在不吸烟的基础上定义了健康的生活方式评分，进行≥210分钟/周的中等/剧烈强度体力活动，轻度到中度饮酒，每天吃蔬菜和水果，体重指数（BMI）为18.5-23.9kg/m2，男性腰臀比（WHR）<0.90，女性<0.85，总分从0到6。
■与具有≤2种健康生活方式因素的参与者相比，有4、5和6个健康生活方式因素的参与者的调整比值比（OR）和95％置信区间（CI）为0.53（95％CI，0.29-0.98），0.40（95%CI，0.21-0.75），和0.36（95%CI，0.16-0.79），分别。只有WHR（OR=0.54，95％CI=0.37-0.78）和体力活动（OR=0.69，95％CI=0.51-0.92）与认知障碍相关。健康的生活方式与整体认知相关(β=0.066，取向(β=0.049)，语言能力（β=0.060），延迟回忆(β=0.045)和执行功能(β=0.044)(P均<0.05)。
■该研究提供了健康生活方式与认知障碍之间负相关的证据。我们调查健康的生活方式是否与特定的认知功能有关，为临床准确处方提供理论依据。
■样本包括2390名社区居住的中国参与者。使用迷你精神状态检查（MMSE）评估他们的认知功能。我们在不吸烟的基础上定义了健康的生活方式评分，进行≥210分钟/周的中等/剧烈强度体力活动，轻度到中度饮酒，每天吃蔬菜和水果，体重指数（BMI）为18.5-23.9kg/m2，男性腰臀比（WHR）<0.90，女性<0.85，总分从0到6。
■与具有≤2种健康生活方式因素的参与者相比，有4、5和6个健康生活方式因素的参与者的调整比值比（OR）和95％置信区间（CI）为0.53（95％CI，0.29-0.98），0.40（95%CI，0.21-0.75），和0.36（95%CI，0.16-0.79），分别。只有WHR（OR=0.54，95％CI=0.37-0.78）和体力活动（OR=0.69，95％CI=0.51-0.92）与认知障碍相关。健康的生活方式与整体认知相关(β=0.066，取向(β=0.049)，语言能力（β=0.060），延迟回忆(β=0.045)和执行功能(β=0.044)(P均<0.05)。
■该研究提供了健康生活方式与认知障碍之间负相关的证据。我们调查健康的生活方式是否与特定的认知功能有关，为临床准确处方提供理论依据。
