PDF(Pubmed)
Abstract：
We investigated how device-measured physical activity (PA) volume (PA energy expenditure [PAEE]) and intensity (fraction of PAEE from moderate-to-vigorous PA [FMVPAEE]) were associated with the incidence of type 2 diabetes mellites (T2DM).
This population-based prospective cohort study included 90,044 participants. The primary exposures were PAEE and FMVPAEE. The secondary exposures were energy expenditure exerted during light, moderate, and vigorous PA and their fraction of PAEE.
Each 1-SD increase in PAEE was associated with a 17% lower risk of T2DM (hazard ratio [HR]: 0.83, 95% confidence interval [CI]: 0.78-0.98). Each 1-SD increase in FMVPAEE was associated with a 21% lower incidence of T2DM (HR: 0.79, 95% CI: 0.74-0.83). Achieving the same PA volume (KJ/kg/day) through vigorous PA (HR: 0.88, 95% CI: 0.85-0.91) was more effective in preventing T2DM than moderate PA (HR: 0.97, 95% CI: 0.96-0.98) and light PA (HR: 0.99, 95% CI: 0.98-1.00).
A higher PA volume is associated with a lower incidence of T2DM. Achieving the same PA volumes through higher-intensity PA is more effective than low-intensity PA in reducing T2DM incidence.
This population-based prospective cohort study included 90,044 participants. The primary exposures were PAEE and FMVPAEE. The secondary exposures were energy expenditure exerted during light, moderate, and vigorous PA and their fraction of PAEE.
Each 1-SD increase in PAEE was associated with a 17% lower risk of T2DM (hazard ratio [HR]: 0.83, 95% confidence interval [CI]: 0.78-0.98). Each 1-SD increase in FMVPAEE was associated with a 21% lower incidence of T2DM (HR: 0.79, 95% CI: 0.74-0.83). Achieving the same PA volume (KJ/kg/day) through vigorous PA (HR: 0.88, 95% CI: 0.85-0.91) was more effective in preventing T2DM than moderate PA (HR: 0.97, 95% CI: 0.96-0.98) and light PA (HR: 0.99, 95% CI: 0.98-1.00).
A higher PA volume is associated with a lower incidence of T2DM. Achieving the same PA volumes through higher-intensity PA is more effective than low-intensity PA in reducing T2DM incidence.
摘要：
■我们调查了器械测量的体力活动(PA)体积(PA能量消耗[PAEE])和强度(来自中度至重度PA[FMVPAEE]的部分PAEE)与2型糖尿病(T2DM)发病率的相关性。
■这项基于人群的前瞻性队列研究包括90,044名参与者。主要暴露于PAEE和FMVPAEE。二次曝光是在光照过程中施加的能量消耗，中度,和有力的PA及其部分的PAEE。
■每增加1-SDPAEE与T2DM风险降低17%相关（风险比[HR]：0.83，95%置信区间[CI]：0.78-0.98）。FMVPAEE的每1-SD增加与T2DM发病率降低21%相关(HR:0.79,95%CI:0.74-0.83)。通过剧烈PA（HR：0.88，95％CI：0.85-0.91）实现相同的PA体积（KJ/kg/天）比中度PA（HR：0.97，95％CI：0.96-0.98）和轻度PA（HR：0.99，95％CI：0.98-1.00）更有效地预防T2DM。
■较高的PA量与较低的T2DM发病率相关。通过较高强度PA实现相同的PA体积在降低T2DM发病率方面比低强度PA更有效。
■这项基于人群的前瞻性队列研究包括90,044名参与者。主要暴露于PAEE和FMVPAEE。二次曝光是在光照过程中施加的能量消耗，中度,和有力的PA及其部分的PAEE。
■每增加1-SDPAEE与T2DM风险降低17%相关（风险比[HR]：0.83，95%置信区间[CI]：0.78-0.98）。FMVPAEE的每1-SD增加与T2DM发病率降低21%相关(HR:0.79,95%CI:0.74-0.83)。通过剧烈PA（HR：0.88，95％CI：0.85-0.91）实现相同的PA体积（KJ/kg/天）比中度PA（HR：0.97，95％CI：0.96-0.98）和轻度PA（HR：0.99，95％CI：0.98-1.00）更有效地预防T2DM。
■较高的PA量与较低的T2DM发病率相关。通过较高强度PA实现相同的PA体积在降低T2DM发病率方面比低强度PA更有效。
