FORGEdb : 用于识别候选功能变体并揭示复杂疾病的靶基因和机制的工具。
关键词: Activity-by-contact (ABC) CRISPR (clustered regularly interspaced short palindromic repeats) DNase-seq Expression quantitative trait locus (eQTL) Functional annotation Gene regulation Genome-wide association study (GWAS) Massively parallel reporter assay (MPRA) Regulatory elements Single guide RNA (sgRNA) Transcription factor (TF) Variant scoring
Mesh : Genome-Wide Association Study Regulatory Sequences, Nucleic Acid Protein Binding Polymorphism, Single Nucleotide
来 源:
DOI:10.1186/s13059-023-03126-1
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