PDF(Pubmed)
Abstract：
BACKGROUND: Recent reviews have reported inconclusive results regarding the usefulness of consuming dates (Phoenix dactylifera L. fruit) in the peripartum period. Hence, this updated systematic review with meta-analysis sought to investigate the efficacy and safety of this integrated intervention in facilitating childbirth and improving perinatal outcomes.
METHODS: Eight data sources were searched comprehensively from their inception until April 30, 2023. Parallel-group randomized and non-randomized controlled trials published in any language were included if conducted during peripartum (i.e., third trimester of pregnancy, late pregnancy, labor, or postpartum) to assess standard care plus oral consumption of dates versus standard care alone or combined with other alternative interventions. The Cochrane Collaboration\'s Risk of Bias (RoB) assessment tools and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) were employed to evaluate the potential RoB and the overall quality of the evidence, respectively. Sufficient data were pooled by a random-effect approach utilizing Stata software.
RESULTS: Of 2,460 records in the initial search, 48 studies reported in 55 publications were included. Data were insufficient for meta-analysis regarding fetal, neonatal, or infant outcomes; nonetheless, most outcomes were not substantially different between dates consumer and standard care groups. However, meta-analyses revealed that dates consumption in late pregnancy significantly shortened the length of gestation and labor, except for the second labor stage; declined the need for labor induction; accelerated spontaneity of delivery; raised cervical dilatation (CD) upon admission, Bishop score, and frequency of spontaneous vaginal delivery. The dates intake in labor also significantly reduced labor duration, except for the third labor stage, and increased CD two hours post-intervention. Moreover, the intervention during postpartum significantly boosted the breast milk quantity and reduced post-delivery hemorrhage. Likewise, dates supplementation in the third trimester of pregnancy significantly increased maternal hemoglobin levels. The overall evidence quality was also unacceptable, and RoB was high in most studies. Furthermore, the intervention\'s safety was recorded only in four trials.
CONCLUSIONS: More well-designed investigations are required to robustly support consuming dates during peripartum as effective and safe integrated care.
BACKGROUND: PROSPERO Registration No: CRD42023399626.
METHODS: Eight data sources were searched comprehensively from their inception until April 30, 2023. Parallel-group randomized and non-randomized controlled trials published in any language were included if conducted during peripartum (i.e., third trimester of pregnancy, late pregnancy, labor, or postpartum) to assess standard care plus oral consumption of dates versus standard care alone or combined with other alternative interventions. The Cochrane Collaboration\'s Risk of Bias (RoB) assessment tools and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) were employed to evaluate the potential RoB and the overall quality of the evidence, respectively. Sufficient data were pooled by a random-effect approach utilizing Stata software.
RESULTS: Of 2,460 records in the initial search, 48 studies reported in 55 publications were included. Data were insufficient for meta-analysis regarding fetal, neonatal, or infant outcomes; nonetheless, most outcomes were not substantially different between dates consumer and standard care groups. However, meta-analyses revealed that dates consumption in late pregnancy significantly shortened the length of gestation and labor, except for the second labor stage; declined the need for labor induction; accelerated spontaneity of delivery; raised cervical dilatation (CD) upon admission, Bishop score, and frequency of spontaneous vaginal delivery. The dates intake in labor also significantly reduced labor duration, except for the third labor stage, and increased CD two hours post-intervention. Moreover, the intervention during postpartum significantly boosted the breast milk quantity and reduced post-delivery hemorrhage. Likewise, dates supplementation in the third trimester of pregnancy significantly increased maternal hemoglobin levels. The overall evidence quality was also unacceptable, and RoB was high in most studies. Furthermore, the intervention\'s safety was recorded only in four trials.
CONCLUSIONS: More well-designed investigations are required to robustly support consuming dates during peripartum as effective and safe integrated care.
BACKGROUND: PROSPERO Registration No: CRD42023399626.
摘要：
背景：最近的评论报道了关于在围产期食用红枣（PhoenixdactyiferaL.fruit）的有用性的不确定结果。因此，本系统综述采用荟萃分析进行了更新,旨在研究这种综合干预措施在促进分娩和改善围产期结局方面的有效性和安全性.
方法：从开始到2023年4月30日，对八个数据源进行了全面搜索。如果在围产期进行，则包括以任何语言发表的平行组随机和非随机对照试验（即，怀孕的第三个三个月，妊娠晚期,劳动,或产后），以评估标准护理加口服红枣与单独标准护理或与其他替代干预措施相结合。Cochrane协作的偏差风险(RoB)评估工具和建议评估分级，发展,和评估（等级）用于评估潜在的RoB和证据的整体质量，分别。利用Stata软件通过随机效应方法汇集足够的数据。
结果：在初始搜索中的2,460条记录中，纳入了55篇出版物中报道的48项研究。数据不足以进行有关胎儿的荟萃分析，新生儿,或婴儿结局；尽管如此，大多数结局在日期消费者和标准护理组之间没有实质性差异.然而,荟萃分析显示，妊娠晚期食用日期显著缩短了妊娠和分娩的时间，除了第二分娩阶段；减少引产的需要；加速自发性分娩；入院时宫颈扩张（CD）升高，主教得分，和自发阴道分娩的频率。劳动中的日期摄入量也显著减少了劳动持续时间，除了第三分娩阶段，并在干预后两小时增加CD。此外，产后干预显著增加了母乳量,减少了产后出血.同样，在妊娠晚期补充日期显著增加母体血红蛋白水平.整体证据质量也是不可接受的，RoB在大多数研究中都很高。此外，仅在4项试验中记录了干预措施的安全性.
结论：需要更多精心设计的调查来有力地支持在围产期食用日期作为有效和安全的综合护理。
背景：PROSPERO注册号：CRD42023399626。
方法：从开始到2023年4月30日，对八个数据源进行了全面搜索。如果在围产期进行，则包括以任何语言发表的平行组随机和非随机对照试验（即，怀孕的第三个三个月，妊娠晚期,劳动,或产后），以评估标准护理加口服红枣与单独标准护理或与其他替代干预措施相结合。Cochrane协作的偏差风险(RoB)评估工具和建议评估分级，发展,和评估（等级）用于评估潜在的RoB和证据的整体质量，分别。利用Stata软件通过随机效应方法汇集足够的数据。
结果：在初始搜索中的2,460条记录中，纳入了55篇出版物中报道的48项研究。数据不足以进行有关胎儿的荟萃分析，新生儿,或婴儿结局；尽管如此，大多数结局在日期消费者和标准护理组之间没有实质性差异.然而,荟萃分析显示，妊娠晚期食用日期显著缩短了妊娠和分娩的时间，除了第二分娩阶段；减少引产的需要；加速自发性分娩；入院时宫颈扩张（CD）升高，主教得分，和自发阴道分娩的频率。劳动中的日期摄入量也显著减少了劳动持续时间，除了第三分娩阶段，并在干预后两小时增加CD。此外，产后干预显著增加了母乳量,减少了产后出血.同样，在妊娠晚期补充日期显著增加母体血红蛋白水平.整体证据质量也是不可接受的，RoB在大多数研究中都很高。此外，仅在4项试验中记录了干预措施的安全性.
结论：需要更多精心设计的调查来有力地支持在围产期食用日期作为有效和安全的综合护理。
背景：PROSPERO注册号：CRD42023399626。
