PDF(Pubmed)
Abstract：
Background After COVID-19 vaccination, females reported irregularities and changes in their menstrual cycle. We aimed to explore the menstrual irregularities following COVID-19 vaccination in Saudi women of childbearing age. Methodology The study was a cross-sectional study conducted among women in Riyadh, Saudi Arabia, who had no history of menstrual irregularities before receiving the first dose of the COVID-19 vaccine. The participants filled out an online self-administered questionnaire via Google Form about any menstrual irregularities they experienced after receiving the COVID-19 vaccine. Results A total of 535 participants completed the survey. The study found that 41.7% (223) of women experienced menstrual changes after the first dose of the COVID-19 vaccine, increasing to 44.1% (236) after the second dose. The incidence of these changes varied between the first and second doses. For example, the incidence of changes in period duration decreased from 51.6% to 48.3% after the first and second doses, respectively. Similarly, the incidence of delayed periods decreased from 48.4% to 47.9%, while dysmenorrhea increased slightly from 30.9% to 32.2% after the two doses. The incidence of heavier menstrual flow increased from 26.9% to 30.5%, while the incidence of lighter menstrual flow decreased from 26.9% to 24.6% after the first and second doses, respectively. Conclusions There is an increased incidence of changes in menstrual cycle after COVID-19 vaccination, particularly in menstrual cycle length, menstrual pain, and the flow of menstruation. Future studies are needed to investigate the potential underlying biological mechanisms.
摘要：
背景在COVID-19疫苗接种后，女性报告月经周期不规则和变化。我们旨在探讨沙特育龄妇女接种COVID-19疫苗后的月经不调。方法这项研究是在利雅得妇女中进行的一项横断面研究，沙特阿拉伯,在接受第一剂COVID-19疫苗之前没有月经不调史。参与者通过谷歌表格填写了一份在线自我管理的问卷，内容是他们在接受COVID-19疫苗后经历的任何月经不调。结果共535名参与者完成调查。研究发现，41.7%(223)的女性在第一次接种COVID-19疫苗后经历了月经变化，在第二剂量后增加到44.1%(236)。这些变化的发生率在第一剂量和第二剂量之间变化。例如,第一次和第二次给药后，持续时间变化的发生率从51.6%下降到48.3%，分别。同样，延迟期的发生率从48.4%下降到47.9%，而痛经在两个剂量后从30.9%略微增加到32.2%。月经量较重的发生率由26.9%上升至30.5%,而在第一次和第二次给药后，月经量较轻的发生率从26.9%下降到24.6%，分别。结论COVID-19疫苗接种后月经周期变化的发生率增加,特别是在月经周期的长度，月经疼痛,和月经的流动。需要进一步的研究来研究潜在的潜在生物学机制。
