PDF(Pubmed)
Abstract：
UNASSIGNED: The high mortality rate of head and neck cancers, particularly oral cancer, poses a significant health challenge in developing nations such as Mongolia. This retrospective survival analysis study was conducted to identify factors influencing the 5-year survival rate of oral squamous cell carcinoma patients.
UNASSIGNED: The study analyzed data from 173 patients diagnosed with oral squamous cell carcinoma, including multiple variables such as age, gender, residence, education, tobacco and alcohol consumption, oral health indicators, family history, precancerous conditions, cancer characteristics, treatment, rehabilitation, cancer recurrence, and 5-year survival. Survival analysis was conducted using the Kaplan-Meier method, and STATA was used for statistical analysis.
UNASSIGNED: The study revealed a 5-year survival rate of 50.3% for oral cancer patients, with a survival rate of 38% for tongue cancer patients. Age, residence, cancer stage, and cancer recurrence were identified as significant survival predictors. Compared to those aged 60 or younger, the hazard ratio (HR) for patients aged 61 or older was 1.52. Survival was associated with female gender (HR = 0.47, CI = 0.29-0.77). Urban residence was associated with decreased survival (HR = 1.92, CI = 1.22-3.05). Significantly worse survival was associated with the presence of cancer recurrence (HR = 1.99, CI = 1.15-3.04). Oral cancer patients in stage IV had a fourfold higher risk of mortality compared to those in stage I (HR = 4.08, CI = 1.2-13.84).
UNASSIGNED: This research highlights the influence of age, urban habitation, and cancer recurrence on oral cancer survival. Age, urban residence, and cancer recurrence were all associated with decreased survival, whereas cancer at stage IV substantially increased the risk of death. The significance of early detection, treatment, and active surveillance to identify oral cancer at an early stage is highlighted by these findings. Compared to industrialized nations, Mongolia\'s lower oral cancer survival rates emphasize the need to increase public awareness and education. A comprehensive approach is required to improve oral cancer patient survival rates and quality of life, including emphasizing early detection through active surveillance, implementing preventive measures, and advancing cancer education initiatives.
UNASSIGNED: The study analyzed data from 173 patients diagnosed with oral squamous cell carcinoma, including multiple variables such as age, gender, residence, education, tobacco and alcohol consumption, oral health indicators, family history, precancerous conditions, cancer characteristics, treatment, rehabilitation, cancer recurrence, and 5-year survival. Survival analysis was conducted using the Kaplan-Meier method, and STATA was used for statistical analysis.
UNASSIGNED: The study revealed a 5-year survival rate of 50.3% for oral cancer patients, with a survival rate of 38% for tongue cancer patients. Age, residence, cancer stage, and cancer recurrence were identified as significant survival predictors. Compared to those aged 60 or younger, the hazard ratio (HR) for patients aged 61 or older was 1.52. Survival was associated with female gender (HR = 0.47, CI = 0.29-0.77). Urban residence was associated with decreased survival (HR = 1.92, CI = 1.22-3.05). Significantly worse survival was associated with the presence of cancer recurrence (HR = 1.99, CI = 1.15-3.04). Oral cancer patients in stage IV had a fourfold higher risk of mortality compared to those in stage I (HR = 4.08, CI = 1.2-13.84).
UNASSIGNED: This research highlights the influence of age, urban habitation, and cancer recurrence on oral cancer survival. Age, urban residence, and cancer recurrence were all associated with decreased survival, whereas cancer at stage IV substantially increased the risk of death. The significance of early detection, treatment, and active surveillance to identify oral cancer at an early stage is highlighted by these findings. Compared to industrialized nations, Mongolia\'s lower oral cancer survival rates emphasize the need to increase public awareness and education. A comprehensive approach is required to improve oral cancer patient survival rates and quality of life, including emphasizing early detection through active surveillance, implementing preventive measures, and advancing cancer education initiatives.
摘要：
■头颈癌的高死亡率，尤其是口腔癌，对蒙古等发展中国家构成了重大的健康挑战。这项回顾性生存分析研究旨在确定影响口腔鳞状细胞癌患者5年生存率的因素。
■该研究分析了173名诊断为口腔鳞状细胞癌的患者的数据，包括多个变量，如年龄，性别,residence,教育,烟草和酒精消费，口腔健康指标,家族史,癌前病变,癌症特征，治疗,康复,癌症复发,5年生存率。使用Kaplan-Meier方法进行生存分析，采用STATA进行统计分析。
■研究显示，口腔癌患者的5年生存率为50.3%，舌癌患者的生存率为38%。年龄,residence,癌症阶段，和癌症复发被确定为显著的生存预测因子。与60岁或以下的人相比，61岁或以上患者的风险比(HR)为1.52.生存率与女性相关（HR=0.47，CI=0.29-0.77）。城市居住与生存率降低相关（HR=1.92，CI=1.22-3.05）。显著恶化的生存率与癌症复发的存在相关(HR=1.99,CI=1.15-3.04)。与I期相比，IV期口腔癌患者的死亡风险高四倍（HR=4.08，CI=1.2-13.84）。
■这项研究强调了年龄的影响，城市居住,和癌症复发对口腔癌生存率的影响。年龄,城市住宅,癌症复发都与生存率下降有关，而IV期癌症显著增加了死亡风险.早期发现的意义,治疗,这些发现强调了在早期阶段积极监测以识别口腔癌。与工业化国家相比，蒙古较低的口腔癌生存率强调了提高公众意识和教育的必要性。需要采取全面的方法来提高口腔癌患者的生存率和生活质量，包括通过主动监测强调早期发现，实施预防措施，推进癌症教育计划。
■该研究分析了173名诊断为口腔鳞状细胞癌的患者的数据，包括多个变量，如年龄，性别,residence,教育,烟草和酒精消费，口腔健康指标,家族史,癌前病变,癌症特征，治疗,康复,癌症复发,5年生存率。使用Kaplan-Meier方法进行生存分析，采用STATA进行统计分析。
■研究显示，口腔癌患者的5年生存率为50.3%，舌癌患者的生存率为38%。年龄,residence,癌症阶段，和癌症复发被确定为显著的生存预测因子。与60岁或以下的人相比，61岁或以上患者的风险比(HR)为1.52.生存率与女性相关（HR=0.47，CI=0.29-0.77）。城市居住与生存率降低相关（HR=1.92，CI=1.22-3.05）。显著恶化的生存率与癌症复发的存在相关(HR=1.99,CI=1.15-3.04)。与I期相比，IV期口腔癌患者的死亡风险高四倍（HR=4.08，CI=1.2-13.84）。
■这项研究强调了年龄的影响，城市居住,和癌症复发对口腔癌生存率的影响。年龄,城市住宅,癌症复发都与生存率下降有关，而IV期癌症显著增加了死亡风险.早期发现的意义,治疗,这些发现强调了在早期阶段积极监测以识别口腔癌。与工业化国家相比，蒙古较低的口腔癌生存率强调了提高公众意识和教育的必要性。需要采取全面的方法来提高口腔癌患者的生存率和生活质量，包括通过主动监测强调早期发现，实施预防措施，推进癌症教育计划。
