METHODS: 16,042 placenta pathology reports between 1997 and 2020 from a tertiary care centre in the Netherlands were retrospectively analysed. For the statistical analysis, the chi-square test and bootstrapping were used to evaluate an association.
RESULTS: In our cohort the prevalence of circumvallate placenta is 2.2 %, placental abruption cases 4.0 % and acute chorioamnionitis 20.6 %. We observed a statistically significant association between all three placental abnormalities: circumvallate placenta, placental abruption and acute chorioamnionitis. In addition, there was also an association between circumvallate placenta and acute chorioamnionitis.
CONCLUSIONS: Our results show that combined presence of circumvallate placenta, placental abruption and acute chorioamnionitis are associated in preterm birth (p = 0.001). A remarkable finding is that the combination of all three abnormalities (circumvallate placenta, placental abruption and acute chorioamnionitis) was not observed in term pregnancies >37 weeks.
方法:回顾性分析了1997年至2020年间荷兰三级护理中心的16,042例胎盘病理报告。对于统计分析,卡方检验和自举试验用于评估相关性.
结果:在我们的队列中,环状胎盘的患病率为2.2%,胎盘早剥4.0%,急性绒毛膜羊膜炎20.6%。我们观察到所有三种胎盘异常之间的统计学显着关联:周围胎盘,胎盘早剥和急性绒毛膜羊膜炎。此外,周围胎盘和急性绒毛膜羊膜炎之间也有关联.
结论:我们的结果表明,合并存在包绕胎盘,胎盘早剥和急性绒毛膜羊膜炎与早产相关(p=0.001)。一个显著的发现是,所有三种异常的组合(周围胎盘,在足月妊娠>37周未观察到胎盘早剥和急性绒毛膜羊膜炎)。