Abstract：
Sleep disorders are commonplace in our modern societies. Specialized hospital departments are generally overloaded, and sleep assessment is an expensive process in terms of equipment, human resources, and time. Biomarkers would usefully complement current measures in the screening and follow-up of sleep disorders and their daytime repercussions. Among salivary markers, a growing body of literature suggests that salivary α-amylase (sAA) may be a cross-species marker of sleep debt. However, there is no consensus as to the direction of variation in sAA with sleep disorders. Herein, after describing the mechanisms of sAA secretion and its relationship with stress, studies assessing the relationship between sAA and sleep parameters are reviewed. Finally, the influence of confounding factors is discussed, along with methodological considerations, to better understand the fluctuations in sAA and facilitate future studies in the field.
摘要：
睡眠障碍在我们的现代社会中司空见惯。专科医院科室普遍超负荷,就设备而言，睡眠评估是一个昂贵的过程，人力资源,和时间。在睡眠障碍及其白天影响的筛查和随访中，生物标志物将有效地补充当前的措施。在唾液标记中，越来越多的文献表明，唾液α-淀粉酶（sAA）可能是睡眠债务的跨物种标记。然而,关于睡眠障碍患者sAA的变化方向尚无共识。在这里，在描述了sAA分泌的机制及其与应激的关系后，综述了评估sAA与睡眠参数之间关系的研究。最后,讨论了混杂因素的影响，以及方法论上的考虑，以更好地了解sAA的波动，并促进该领域的未来研究。
