PDF(Pubmed)
Abstract：
OBJECTIVE: To evaluate the relationship between fungal infection in the female genital tract and infertility.
METHODS: A systematic review was carried out, and the search was conducted in Medline, Embase, Web of Science, Google Scholar, and Cochrane Library databases until August 2022. The search strategy used standardized keywords such as \"candidiasis\" and \"infertility,\" combined with their respective synonyms. The search was limited to human studies, with no language restrictions.
METHODS: Primary articles that evaluated women of reproductive age with and without infertility and related to the presence or absence of candidiasis were included.
METHODS: For the analyses, the odds ratio association measure was used with a confidence interval of 95% using RevMan software (version 5.4).
RESULTS: Eight studies, published between 1995 and 2021 in different countries around the world, were included in this systematic review. Two studies were excluded after sensitivity analysis. A total of 909 participants were included in the group of infertile women and 2363 women in the control group. The age of the evaluated women varied between 18 and 50 years. The random effect model was used and showed no significant difference when comparing candidiasis between fertile and infertile women (odds ratio: 1.44; 95% confidence interval 0.86, 2.41 p= 0.17).
CONCLUSIONS: There was no association between candidiasis and female sterility.
METHODS: A systematic review was carried out, and the search was conducted in Medline, Embase, Web of Science, Google Scholar, and Cochrane Library databases until August 2022. The search strategy used standardized keywords such as \"candidiasis\" and \"infertility,\" combined with their respective synonyms. The search was limited to human studies, with no language restrictions.
METHODS: Primary articles that evaluated women of reproductive age with and without infertility and related to the presence or absence of candidiasis were included.
METHODS: For the analyses, the odds ratio association measure was used with a confidence interval of 95% using RevMan software (version 5.4).
RESULTS: Eight studies, published between 1995 and 2021 in different countries around the world, were included in this systematic review. Two studies were excluded after sensitivity analysis. A total of 909 participants were included in the group of infertile women and 2363 women in the control group. The age of the evaluated women varied between 18 and 50 years. The random effect model was used and showed no significant difference when comparing candidiasis between fertile and infertile women (odds ratio: 1.44; 95% confidence interval 0.86, 2.41 p= 0.17).
CONCLUSIONS: There was no association between candidiasis and female sterility.
摘要：
目的：探讨女性生殖道真菌感染与不孕症的关系。
方法：进行了系统评价，搜索是在Medline进行的,Embase,WebofScience,谷歌学者，和Cochrane图书馆数据库，直到2022年8月。搜索策略使用标准化的关键词，如“念珠菌病”和“不孕症”，\"结合各自的同义词。搜索仅限于人类研究，没有语言限制。
方法：包括评估育龄妇女有无不育症以及是否存在念珠菌病的主要文章。
方法：对于分析，使用RevMan软件(5.4版),比值比关联测量的置信区间为95%.
结果：八项研究，1995年至2021年在世界不同国家出版，被纳入本系统综述。敏感性分析后排除了两项研究。共有909名参与者被纳入不育妇女组，2363名妇女被纳入对照组。被评估妇女的年龄在18至50岁之间。使用随机效应模型，在比较可育和不育妇女之间的念珠菌病时没有显着差异（比值比：1.44；95％置信区间0.86，2.41p=0.17）。
结论：念珠菌病与女性不育症之间没有关联。
方法：进行了系统评价，搜索是在Medline进行的,Embase,WebofScience,谷歌学者，和Cochrane图书馆数据库，直到2022年8月。搜索策略使用标准化的关键词，如“念珠菌病”和“不孕症”，\"结合各自的同义词。搜索仅限于人类研究，没有语言限制。
方法：包括评估育龄妇女有无不育症以及是否存在念珠菌病的主要文章。
方法：对于分析，使用RevMan软件(5.4版),比值比关联测量的置信区间为95%.
结果：八项研究，1995年至2021年在世界不同国家出版，被纳入本系统综述。敏感性分析后排除了两项研究。共有909名参与者被纳入不育妇女组，2363名妇女被纳入对照组。被评估妇女的年龄在18至50岁之间。使用随机效应模型，在比较可育和不育妇女之间的念珠菌病时没有显着差异（比值比：1.44；95％置信区间0.86，2.41p=0.17）。
结论：念珠菌病与女性不育症之间没有关联。
