Mesh : Humans Female Child Antifungal Agents / therapeutic use Celiac Disease / complications diagnosis Cystic Fibrosis / complications drug therapy Zygomycosis / complications diagnosis drug therapy Intraabdominal Infections / drug therapy

来  源:   DOI:10.4269/ajtmh.23-0404   PDF(Pubmed)

Abstract:
Basidiobolomycosis is an uncommon fungal infection that has been reported in the literature mainly as a cause of infection in the skin and subcutaneous tissue. Intraabdominal infections have been reported in tropical and subtropical areas in the Middle East, such as Iran and Saudi Arabia, and in the United States. Our patient was a 6-year-old girl with cystic fibrosis and celiac disease who was referred to our department with a history of chronic abdominal pain. In the imaging studies of the abdomen and pelvis, a large retroperitoneal mass was reported in the right upper part of the abdomen with involvement of the duodenum and the mesentery of the small and large intestines, as well as the superior mesenteric vessels, and was diagnosed as basidiobolomycosis through biopsy. Because of the large unresectable mass, the patient was first treated with antifungal drugs for 2 months and then surgical resection was performed. The main point in the management of these patients is a combination of antifungal therapy and surgical resection. In some patients, complex surgeries such as the Whipple procedure may be performed to appropriately manage intraabdominal infections.
摘要:
基底细菌病是一种罕见的真菌感染,在文献中已报道主要是皮肤和皮下组织感染的原因。据报道,中东的热带和亚热带地区有腹内感染,比如伊朗和沙特阿拉伯,在美国。我们的患者是一名患有囊性纤维化和乳糜泻的6岁女孩,她被转诊到我们部门,有慢性腹痛史。在腹部和骨盆的影像学研究中,据报道,在腹部右上部有一个大的腹膜后肿块,累及十二指肠和小肠的肠系膜,以及肠系膜上血管,并通过活检诊断为基底细菌病。因为巨大的不可切除的质量,患者首先接受抗真菌药物治疗2个月,然后进行手术切除.这些患者的治疗要点是抗真菌治疗和手术切除的结合。在一些患者中,可以进行复杂的手术,例如Whipple手术,以适当地管理腹腔内感染。
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