Abstract：
Osteoid osteoma is one of the most frequent benign musculoskeletal neoplasm. Radiofrequency ablation is the method of choice for non-conservative treatment of osteoid osteoma. Recently, high-intensity focused ultrasound (HIFU) has been proposed as a safer option. The objective of this study is to review the efficacy and side effects of HIFU in the management of osteoid osteoma. A comprehensive search was conducted in PubMed, Science Direct, and Clinical Key until June 30, 2022. Demographic data, baseline characteristics, success rates, pre- and post-procedure pain scores, recurrences, and complications were recorded. Eleven studies were included in this systematic review. Pooled analysis that involved 186 subjects resulted in an overall success rate of 91.94%. Recurrence was reported in two studies, in which it occurred in 4/177 (2.26%) subjects. Skin burn was found in 1 (0.54%) patients. No major or other complications were reported. Three studies compared the success rate of HIFU and RFA. Success rate was slightly higher in the RFA group with insignificant difference (p = 0.15). High-intensity focused ultrasound showed promising results. It offers a safer treatment approach for osteoid osteoma, especially in children, and can be considered for recalcitrant cases after RFA. Nonetheless, more studies are expected in the future.
摘要：
骨样骨瘤是最常见的良性肌肉骨骼肿瘤之一。射频消融是非保守治疗骨样骨瘤的首选方法。最近,高强度聚焦超声（HIFU）已被提出作为一种更安全的选择。本研究的目的是回顾HIFU在骨样骨瘤治疗中的疗效和副作用。在PubMed进行了全面搜索，科学直接，和临床关键，直到2022年6月30日。人口统计数据,基线特征，成功率,术前和术后疼痛评分，复发，并记录并发症。本系统综述包括11项研究。涉及186名受试者的汇总分析的总体成功率为91.94%。在两项研究中报告了复发，其中发生在4/177（2.26%）受试者中。皮肤烧伤1例(0.54%)。未报告重大或其他并发症。三项研究比较了HIFU和RFA的成功率。RFA组的成功率略高，差异无统计学意义（p=0.15）。高强度聚焦超声显示了有希望的结果。它为骨样骨瘤提供了一种更安全的治疗方法，尤其是在儿童中，并且可以考虑RFA后的顽固性病例。尽管如此，预计将来会有更多的研究。
