Abstract：
OBJECTIVE: To explore the feasibility for a set of hormone replacement therapy (HRT) eligibility guidelines that follow a similar structure and appearance to the UKMEC guidance for contraception. To enable non-specialists to feel confident in safely prescribing HRT and to aid selection of the most appropriate first line treatment.
METHODS: A literature review was undertaken with evidence summarised on the topic of venous thromboembolism (VTE) which is an area frequently considered a barrier to prescribing. Medical eligibility tables which separated HRT by type were then produced for a set of VTE-related topics.
RESULTS: The literature search confirmed the importance of distinguishing between different types and routes of administration when considering the suitability of HRT. Much of the evidence has been based on older synthetic types of HRT and whilst they still have a role in management, these medications carry different risks to the now more accepted use of body identical types. The search also highlighted the nuances involved, increasing the complexity of forming guidelines, with the need for consideration to be given to an individual\'s own perception of risks and benefits.
CONCLUSIONS: The demand for HRT has risen in recent years and there is a need for this to be managed effectively, particularly for patients in primary care. The production of this type of guidance will enable the non-specialist to feel confident in safe and evidence-based prescribing. The guidelines are also designed to demonstrate to prescribers which complex patients should be referred onto menopause specialists.
METHODS: A literature review was undertaken with evidence summarised on the topic of venous thromboembolism (VTE) which is an area frequently considered a barrier to prescribing. Medical eligibility tables which separated HRT by type were then produced for a set of VTE-related topics.
RESULTS: The literature search confirmed the importance of distinguishing between different types and routes of administration when considering the suitability of HRT. Much of the evidence has been based on older synthetic types of HRT and whilst they still have a role in management, these medications carry different risks to the now more accepted use of body identical types. The search also highlighted the nuances involved, increasing the complexity of forming guidelines, with the need for consideration to be given to an individual\'s own perception of risks and benefits.
CONCLUSIONS: The demand for HRT has risen in recent years and there is a need for this to be managed effectively, particularly for patients in primary care. The production of this type of guidance will enable the non-specialist to feel confident in safe and evidence-based prescribing. The guidelines are also designed to demonstrate to prescribers which complex patients should be referred onto menopause specialists.
摘要：
目的：探索一套激素替代疗法（HRT）合格指南的可行性，该指南遵循与UKMEC避孕指南相似的结构和外观。使非专业人员能够对安全开HRT并帮助选择最合适的一线治疗方法充满信心。
方法：进行了文献综述，总结了静脉血栓栓塞（VTE）这一领域的证据。然后为一组与VTE相关的主题制作了按类型分隔HRT的医疗资格表。
结果：文献检索证实了在考虑HRT的适用性时区分不同类型和给药途径的重要性。许多证据都是基于较旧的合成类型的HRT，虽然它们仍然在管理中发挥作用，这些药物具有不同的风险，现在更被接受的使用身体相同的类型。搜索还突出了其中的细微差别，增加了形成准则的复杂性，需要考虑个人对风险和收益的看法。
结论：近年来，对HRT的需求有所增加，需要对此进行有效管理，特别是初级保健患者。这种类型的指导的产生将使非专业人员对安全和基于证据的处方充满信心。该指南还旨在向处方者证明哪些复杂患者应转诊至更年期专家。
方法：进行了文献综述，总结了静脉血栓栓塞（VTE）这一领域的证据。然后为一组与VTE相关的主题制作了按类型分隔HRT的医疗资格表。
结果：文献检索证实了在考虑HRT的适用性时区分不同类型和给药途径的重要性。许多证据都是基于较旧的合成类型的HRT，虽然它们仍然在管理中发挥作用，这些药物具有不同的风险，现在更被接受的使用身体相同的类型。搜索还突出了其中的细微差别，增加了形成准则的复杂性，需要考虑个人对风险和收益的看法。
结论：近年来，对HRT的需求有所增加，需要对此进行有效管理，特别是初级保健患者。这种类型的指导的产生将使非专业人员对安全和基于证据的处方充满信心。该指南还旨在向处方者证明哪些复杂患者应转诊至更年期专家。
