Abstract：
OBJECTIVE: To analyse the comparative clinical outcomes and clinicopathological significance of vocal fold leukoplakia lesions treated by appearance classification and traditional methods.
METHODS: A total of 1442 vocal fold leukoplakia patients were enrolled. Group A patients were treated according to appearance classification and Group B patients were treated according to traditional methods.
RESULTS: In Group A, 24.4, 14.9 and 60.6 per cent of patients had grade I, II and III dysplasia, respectively. Grade I dysplasia (63.4 per cent) was more than twice as frequent in Group B patients than in Group A patients, while grade II dysplasia (20.4 per cent) and grade III dysplasia (16.2 per cent) were significantly less frequent in Group B patients than in Group A patients (p = 0.000). There was a significant correlation between vocal fold leukoplakia appearance and the degree of dysplasia (p = 0.000). The recurrence and malignant transformation rates (17.6 and 31 per cent, respectively) in Group B were significantly greater than those in Group A (10.8 and 25.9 per cent, respectively) (p = 0.000).
CONCLUSIONS: Vocal fold leukoplakia appearance classification is useful for guiding treatment decision-making and could help to improve therapeutic accuracy.
METHODS: A total of 1442 vocal fold leukoplakia patients were enrolled. Group A patients were treated according to appearance classification and Group B patients were treated according to traditional methods.
RESULTS: In Group A, 24.4, 14.9 and 60.6 per cent of patients had grade I, II and III dysplasia, respectively. Grade I dysplasia (63.4 per cent) was more than twice as frequent in Group B patients than in Group A patients, while grade II dysplasia (20.4 per cent) and grade III dysplasia (16.2 per cent) were significantly less frequent in Group B patients than in Group A patients (p = 0.000). There was a significant correlation between vocal fold leukoplakia appearance and the degree of dysplasia (p = 0.000). The recurrence and malignant transformation rates (17.6 and 31 per cent, respectively) in Group B were significantly greater than those in Group A (10.8 and 25.9 per cent, respectively) (p = 0.000).
CONCLUSIONS: Vocal fold leukoplakia appearance classification is useful for guiding treatment decision-making and could help to improve therapeutic accuracy.
摘要：
目的：分析声带白斑的外观分型与传统方法治疗的临床疗效及临床病理意义。
方法：共纳入1442例声带白斑患者。A组患者按外观分型进行治疗,B组患者按传统方法进行治疗。
结果：在A组中，24.4,14.9%和60.6%的病人为一级,II和III发育不良，分别。一级发育不良(63.4%)在乙组患者中的频率是甲组患者的两倍多,而B组患者中II级发育不良(20.4%)和III级发育不良(16.2%)的发生率明显低于A组患者(p=0.000)。声带白斑的外观与发育不良程度之间存在显着相关性（p=0.000）。复发率和恶变率(17.6%和31%,分别)B组显著高于A组(10.8%和25.9%，分别)(p=0.000)。
结论：声带白斑外观分类有助于指导治疗决策，并有助于提高治疗准确性。
方法：共纳入1442例声带白斑患者。A组患者按外观分型进行治疗,B组患者按传统方法进行治疗。
结果：在A组中，24.4,14.9%和60.6%的病人为一级,II和III发育不良，分别。一级发育不良(63.4%)在乙组患者中的频率是甲组患者的两倍多,而B组患者中II级发育不良(20.4%)和III级发育不良(16.2%)的发生率明显低于A组患者(p=0.000)。声带白斑的外观与发育不良程度之间存在显着相关性（p=0.000）。复发率和恶变率(17.6%和31%,分别)B组显著高于A组(10.8%和25.9%，分别)(p=0.000)。
结论：声带白斑外观分类有助于指导治疗决策，并有助于提高治疗准确性。
