METHODS: A total of 1442 vocal fold leukoplakia patients were enrolled. Group A patients were treated according to appearance classification and Group B patients were treated according to traditional methods.
RESULTS: In Group A, 24.4, 14.9 and 60.6 per cent of patients had grade I, II and III dysplasia, respectively. Grade I dysplasia (63.4 per cent) was more than twice as frequent in Group B patients than in Group A patients, while grade II dysplasia (20.4 per cent) and grade III dysplasia (16.2 per cent) were significantly less frequent in Group B patients than in Group A patients (p = 0.000). There was a significant correlation between vocal fold leukoplakia appearance and the degree of dysplasia (p = 0.000). The recurrence and malignant transformation rates (17.6 and 31 per cent, respectively) in Group B were significantly greater than those in Group A (10.8 and 25.9 per cent, respectively) (p = 0.000).
CONCLUSIONS: Vocal fold leukoplakia appearance classification is useful for guiding treatment decision-making and could help to improve therapeutic accuracy.
方法:共纳入1442例声带白斑患者。A组患者按外观分型进行治疗,B组患者按传统方法进行治疗。
结果:在A组中,24.4,14.9%和60.6%的病人为一级,II和III发育不良,分别。一级发育不良(63.4%)在乙组患者中的频率是甲组患者的两倍多,而B组患者中II级发育不良(20.4%)和III级发育不良(16.2%)的发生率明显低于A组患者(p=0.000)。声带白斑的外观与发育不良程度之间存在显着相关性(p=0.000)。复发率和恶变率(17.6%和31%,分别)B组显著高于A组(10.8%和25.9%,分别)(p=0.000)。
结论:声带白斑外观分类有助于指导治疗决策,并有助于提高治疗准确性。