Abstract：
Full-thickness macular hole (FTMH) is a debilitating retinal disorder, particularly in its advanced forms, necessitating surgical intervention for vision restoration. This case report details the successful closure of a large FTMH using the inverted flap technique, highlighting the essential role of multimodal imaging, and particularly macular pigment optical density (MPOD) assessment, in preoperative and postoperative evaluation. A 55-year-old patient presented with severe vision loss in one eye due to a large FTMH. Surgery was performed by an expert vitreoretinal surgeon, resulting in significant postoperative improvements in visual acuity and retinal architecture. Multimodal imaging, including MPOD assessment, played a pivotal role in preoperative evaluation and postoperative monitoring. The notable increase in MPOD following successful surgery suggests its potential role as a valuable adjunctive biomarker associated with a good visual prognosis following this type of macular hole surgical interventions.
摘要：
全层黄斑裂孔（FTMH）是一种使人衰弱的视网膜疾病，特别是其先进的形式，需要手术干预以恢复视力。此病例报告详细说明了使用倒置皮瓣技术成功闭合大型FTMH，强调多模态成像的重要作用，特别是黄斑色素光密度（MPOD）评估，在术前和术后评估中。一名55岁的患者由于FTMH大，一只眼睛出现严重的视力丧失。手术由专业的玻璃体视网膜外科医生进行，导致术后视力和视网膜结构的显着改善。多模态成像,包括MPOD评估，在术前评估和术后监测中发挥了重要作用。成功手术后MPOD的显着增加表明其作为有价值的辅助生物标志物的潜在作用，与这种类型的黄斑孔手术干预后的良好视觉预后相关。
