PDF(Pubmed)
Abstract：
Mercury has been described as been in daily household items such as soaps, skin-lightening creams (SLC), and topical disinfectants. Mercury exposure can reportedly cause damage to the optic nerve and retina. A 30-year-old Somali woman presented with decreased vision and was found to have bilateral optic atrophy. Neuroimaging and laboratory work-up for nutritional deficiencies, heavy metals, and syphilis were performed. Evaluation revealed normal neuroimaging and laboratory work-up except for elevated serum and urine mercury levels. Mercury levels at the initial blood test was 11.1 ug/L (normal limits < 10.0 ug/L) and was 15.7 ug/L on repeat testing. A 24-h urine test showed elevated mercury at 16 ug/24 h (normal limits < 2 ug/24 h). Evaluation of an unlabelled SLC that she was using showed the presence of mercury. It is worth testing for heavy metals in the work-up of bilateral optic atrophy. Clinicians should consider cosmetic products as a potential source of mercury exposure and recommend discontinuation if mercury is present.
摘要：
汞被描述为日常家居用品，如肥皂，美白霜(SLC),和局部消毒剂。据报道，汞暴露会对视神经和视网膜造成损害。一名30岁的索马里妇女视力下降，被发现患有双侧视神经萎缩。营养缺乏的神经影像学和实验室检查，重金属,和梅毒。评估显示神经影像学和实验室检查正常，但血清和尿汞水平升高。初始血液测试时的汞水平为11.1ug/L（正常限值<10.0ug/L），重复测试时为15.7ug/L。24小时尿检显示汞在16ug/24小时升高（正常限度<2ug/24小时）。对她正在使用的未标记SLC的评估显示存在汞。值得在双侧视神经萎缩的工作中测试重金属。临床医生应将化妆品视为汞暴露的潜在来源，如果存在汞，则建议停止使用。
