Abstract：
The purpose of this study is to analyze the early clinical features of coronary artery lesion (CAL) in Kawasaki disease (KD), evaluate systemic inflammation indicators, and enhance early recognition of CAL in the acute phase of KD. A total of 314 children with KD were divided into those with CAL (CAL group) and without CAL (NCAL group) using echocardiographic results, and their clinical data were retrospectively analyzed. For KD patients, male, children aged 3 to 9 years, and those with fever longer than 6 days before intravenous immunoglobulin (IVIG) use were more likely to have CAL. There were significant differences in sex, age, and fever time (P < .05). Moreover, some laboratory indicator test results revealed there was a significant difference between N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and interleukin-6 (IL-6), and the CAL (P < .05). This study has certain guiding significance for early clinical evaluation.
摘要：
目的分析川崎病(KD)冠状动脉病变(CAL)的早期临床特点,评估全身炎症指标，并在KD急性期增强CAL的早期识别。根据超声心动图结果，将314例KD患儿分为CAL组（CAL组）和非CAL组（NCAL组）。并对其临床资料进行回顾性分析。对于KD患者，男性,3至9岁的儿童，那些在使用静脉注射免疫球蛋白（IVIG）之前发烧超过6天的人更有可能患有CAL。性别差异显著,年龄,发热时间(P<0.05)。此外，一些实验室指标检测结果显示，N末端脑钠肽前体（NT-pro-BNP）和白细胞介素-6（IL-6）之间存在显着差异，和CAL(P<.05)。本研究对早期临床评价具有一定的指导意义。
