关键词: Cervical Equine Infiltrative blockade Lidocaine Neurologic disease

Mesh : Humans Animals Horses Anesthetics Lidocaine / pharmacology

来  源:   DOI:10.1016/j.jevs.2023.104987

Abstract:
The analysis of cerebrospinal fluid has diagnostic, prognostic, and therapeutic value in neurological illnesses in horses. There are different methods for obtaining cerebrospinal fluid, with the collection between the C1 and C2 vertebrae being a more recent methodology, which allows the procedure to be performed in standing patients, without the limitations of general anesthesia and with a low contamination of the sample with blood, presenting itself as a practical alternative. This study evaluated the efficacy and safety of a local dural blockade in healthy horses submitted to cerebrospinal fluid collection by atlantoaxial puncture and the quality of the samples obtained by this procedure, which were submitted to physical, chemical, and cytological analyses. The animals were evaluated considering aspects such as pain, sensitivity, the presence of edema, temperature variations, and ultrasonographic alterations post-collection. Discrete local changes were observed after the puncture, and the procedure was considered safe and simple to perform. Lidocaine blockade could reduce the reaction elicited by the needle passing through the dura mater, and the samples obtained showed satisfactory quality and laboratory results consistent with the values compiled in the literature. Transient hyperthermia was observed in 70% (7/10) of the animals in the dural blockade group, and 80%(8/10) of the patients from the control group, totalizing 75% of all individuals evaluated. The rectal temperature alteration was observed 4 to 12 hours after the procedure and was entirely resolved without intervention by the 24-hour evaluation.
摘要:
脑脊液的分析有诊断意义,预后,和治疗马的神经系统疾病的价值。有不同的获取脑脊液的方法,C1和C2椎骨之间的收集是一种较新的方法,这使得手术可以在站立的病人身上进行,没有全身麻醉的限制,并且血液对样品的污染较低,把自己作为一个实际的选择。这项研究评估了通过寰枢椎穿刺进行脑脊液收集的健康马匹的局部硬脑膜阻滞的有效性和安全性,以及通过该程序获得的样品的质量。被提交给身体,化学,和细胞学分析。考虑到疼痛等方面对动物进行评估,灵敏度,水肿的存在,温度变化,和收集后的超声改变。穿刺后观察到局部离散变化,并且该程序被认为是安全且易于执行的。利多卡因阻滞可以减少针头通过硬脑膜引起的反应,获得的样品显示出令人满意的质量,实验室结果与文献中汇编的值一致。在硬脑膜阻滞组的动物中有70%(7/10)观察到短暂的高温,和80%(8/10)的患者来自对照组,总共75%的个体被评估。手术后4至12小时观察到直肠温度的变化,并且在没有干预的情况下通过24小时评估完全解决。
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